Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06439095
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2024-06-03
First Post:
2024-05-27
Brief Title:
Interleukin-2 IL-2 Interleukin-5 IL-5 and Interleukin-17 IL-17 Levels of Patients With Stainless Steel Crowns
Sponsor:
Yuzuncu Yıl University
Organization:
Yuzuncu Yıl University
Study Overview
Official Title:
Evaluation of IL-2 IL-5 and IL-17 Expression Levels in Saliva of Patients Treated With Stainless Steel Crowns
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate whether nickel hypersensitivity following stainless steel crown treatment in children aged 7-13 leads to an increase in IL-2 IL-5 and IL-17 levels by analyzing saliva samples By doing so the study seeks to prevent potential hypersensitivity reactions after stainless steel crown treatment
The main question it aims to answer is
Which interleukin level increases in the controls 1 week after stainless steel crowns are applied Researchers will investigate whether there is a significant increase in interleukin levels in childrens saliva before and after the procedure
Participants will
They will provide saliva samples before stainless steel crowns are applied They will visit the clinic after 1 week for check-ups and tests
The main question it aims to answer is
Which interleukin level increases in the controls 1 week after stainless steel crowns are applied Researchers will investigate whether there is a significant increase in interleukin levels in childrens saliva before and after the procedure
Participants will
They will provide saliva samples before stainless steel crowns are applied They will visit the clinic after 1 week for check-ups and tests
Detailed Description:
Expression levels of IL-2 IL-5 and IL-17 in the saliva of individuals aged 7-13 years who underwent stainless steel crown will be recorded before and after the procedure Before the saliva sample collection procedure the patient will be asked to rinse their mouth with sterile water and then spit into sterile plastic cups After collecting approximately 3 ml of saliva the saliva will be transferred to appropriate eppendorfs and stored at -40 degrees Celsius For the second post-procedure the same algorithms will be applied for saliva collection seven days after the crown procedure Also ph value and ion levels of saliva will be measured
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None