Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06434766
Status:
RECRUITING
Last Update Posted:
2024-07-09
First Post:
2024-05-15
Brief Title:
Multicenter iTBS Neuromodulation for PTSD Treatment
Sponsor:
Second Affiliated Hospital School of Medicine Zhejiang University
Organization:
Second Affiliated Hospital School of Medicine Zhejiang University
Study Overview
Official Title:
A Multicenter Clinical Study on Transcranial Magnetic Stimulation of the Primary Motor Cortex for PTSD Treatment
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TMCP
Brief Summary:
The proposed study aims to evaluate the efficacy of intermittent theta-burst transcranial magnetic stimulation iTBS targeting primary motor cortex M1 as adjunct treatment for PTSD patients The primary outcome measure includes changes in PTSD symptom severity with secondary outcome measures focusing on negative moods improvements quality of life and socialoccupation functioning and functional connectivity of the brain
Detailed Description:
The proposed study aims to evaluate the efficacy of intermittent theta-burst transcranial magnetic stimulation iTBS targeting primary motor cortex as adjunct treatment for PTSD patients
Compared to traditional repetitive transcranial magnetic stimulation rTMS iTBS strategy usually delivers large amounts of pulses in a shorter time period and its equal efficiency has been demonstrated in several psychiatric disorders such as major depressive disorder MDD Through this adequately randomized and sham-controlled study of iTBS for PTSD this work will provide an alternative and potentially more potent stimulation target for clinical PTSD treatment This study will also provide a comprehensive assessment of this treatment strategy towards improvements in symptoms quality of life and brain functioning in PTSD
The ultimate goal of this study is to develop a non-invasive brain stimulation approach targeting a novel site for alleviating symptoms and improving life quality for PTSD patients
Compared to traditional repetitive transcranial magnetic stimulation rTMS iTBS strategy usually delivers large amounts of pulses in a shorter time period and its equal efficiency has been demonstrated in several psychiatric disorders such as major depressive disorder MDD Through this adequately randomized and sham-controlled study of iTBS for PTSD this work will provide an alternative and potentially more potent stimulation target for clinical PTSD treatment This study will also provide a comprehensive assessment of this treatment strategy towards improvements in symptoms quality of life and brain functioning in PTSD
The ultimate goal of this study is to develop a non-invasive brain stimulation approach targeting a novel site for alleviating symptoms and improving life quality for PTSD patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None