Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06434155
Status:
COMPLETED
Last Update Posted:
2024-05-30
First Post:
2024-05-20
Brief Title:
Social History and Glaucoma Progression
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Social History and Glaucoma Progression The Effect of Body Mass Index Tobacco and Alcohol Consumption on the Rates of Structural Change in Patients With Open Angle Glaucoma
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OCT
Brief Summary:
The objective of this study is to predict of glaucoma progression By imaging of the retinal nerve fiber layer RNFL optic nerve head ONH and macular measurements using spectral-domain OCT SD-OCT instruments
Detailed Description:
Glaucoma is a multifactorial optic neuropathy characterized by structural damage of retinal ganglion cells RGCs and their axons that is associated with vision loss and may lead to irreversible blindness Because glaucomatous damage is irreversible and effective treatment is available to halt further damage glaucoma management should be optimized with precise micrometer-scale quantifications of ocular structures that improve detection of the disease and its progression The introduction of OCT technology more than 20 years ago provided in vivo detailed visualization of the optic nerve head ONH and retina and enabled the quantitative evaluation of these tructures Circumpapillary retinal nerve fiber layer RNFL thickness is a common OCT measurement that provides comprehensive evaluation of all RGCs in an eye as they converge into the ONH
When measured with spectral-domain OCT the RNFL has been shown to differentiate between healthy and glaucomatous eyes The steady evolution of OCT technology has led to imaging with better resolution higher scanning speeds and advanced imaging patterns that has improved the reliability of OCT measurements and allowed for detection of minute changes that can improve the sensitivity of progression detection Assessment of glaucoma progression usually is based on event or trend analysis Event-based progression determines when a measurement exceeds a pre-established threshold for change from baseline Trend-based analysis quantifies the rate of a parameters progression over time
When measured with spectral-domain OCT the RNFL has been shown to differentiate between healthy and glaucomatous eyes The steady evolution of OCT technology has led to imaging with better resolution higher scanning speeds and advanced imaging patterns that has improved the reliability of OCT measurements and allowed for detection of minute changes that can improve the sensitivity of progression detection Assessment of glaucoma progression usually is based on event or trend analysis Event-based progression determines when a measurement exceeds a pre-established threshold for change from baseline Trend-based analysis quantifies the rate of a parameters progression over time
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None