Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06432491
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-29
First Post:
2024-05-01
Brief Title:
The Association Between Core Temperature and Health
Sponsor:
Shenzhen Institute of Advanced Technology Chinese Academy of Sciences
Organization:
Shenzhen Institute of Advanced Technology Chinese Academy of Sciences
Study Overview
Official Title:
Study to Explore How Core Temperature Reduction Influence Health
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to learn if cold water drinking could promote body composition and further extend healthy lifespan in Chinese older adults The main questions it aims to answer are
1 Does cold water drinking lower the body fat percentage
2 Will cold water drinking positively extend lifespan in a long-term Researchers will compare cold water intervention group to a control group drinking 37 water instead to see if cold water drinking works to promote health and slow down ageing process
Participants will
1 Drink 4 or 37 water 4 times 9am 12pm 15pm 18pm every day for 6 months
2 Visit the institute and health checkup department for tests and checkup at baseline the end of the 3rd month and the end of 6th month
1 Does cold water drinking lower the body fat percentage
2 Will cold water drinking positively extend lifespan in a long-term Researchers will compare cold water intervention group to a control group drinking 37 water instead to see if cold water drinking works to promote health and slow down ageing process
Participants will
1 Drink 4 or 37 water 4 times 9am 12pm 15pm 18pm every day for 6 months
2 Visit the institute and health checkup department for tests and checkup at baseline the end of the 3rd month and the end of 6th month
Detailed Description:
According to pilot study we found 4 water could significantly reduce core body temperature Thus we aim to explore whether 4 water drinking could promote body composition and further help to extend lifespan
Participants will be randomly divided into intervention drinking 4 water at 9am 12pm 15pm 18pm and control group drinking 37 water at 9am 12pm 15pm 18pm for 6-month intervention Tests will be conducted in Shenzhen Institute of Advanced Technology while checkup will be tested at Health Checkup Department of Shenzhen University General Hospital Body composition will be tested by Magnetic Resonance Imaging MRI Dual-Energy X-Ray Absorptiometry DEXA and TANITA bioelectrical method In addition we will test participants waist and hip circumferences using 3D scanning Besides we will test core body temperature and brown adipose tissue
Apart from above main outcomes we will also test their physical activity food intake metabolic rate glucose IL-6 TNF-alpha HDL LDL insulin level Meanwhile ageing biomarkers namely Phenotypic Age eye fundus image facial changes bone density gut microbiota GlycanAge will also be measured
The whole intervention period will last for 6 months All the tests and checkup will be tested at baseline the end of the third month and the endpoint of the study
Participants will be randomly divided into intervention drinking 4 water at 9am 12pm 15pm 18pm and control group drinking 37 water at 9am 12pm 15pm 18pm for 6-month intervention Tests will be conducted in Shenzhen Institute of Advanced Technology while checkup will be tested at Health Checkup Department of Shenzhen University General Hospital Body composition will be tested by Magnetic Resonance Imaging MRI Dual-Energy X-Ray Absorptiometry DEXA and TANITA bioelectrical method In addition we will test participants waist and hip circumferences using 3D scanning Besides we will test core body temperature and brown adipose tissue
Apart from above main outcomes we will also test their physical activity food intake metabolic rate glucose IL-6 TNF-alpha HDL LDL insulin level Meanwhile ageing biomarkers namely Phenotypic Age eye fundus image facial changes bone density gut microbiota GlycanAge will also be measured
The whole intervention period will last for 6 months All the tests and checkup will be tested at baseline the end of the third month and the endpoint of the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None