Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06439212
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-03
First Post:
2024-05-18
Brief Title:
the Efficacy of Ginger Powder as an Analgesic for Intraoperative and Post- Endodontic Pain Management
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Assessing the Efficacy of Ginger Powder Capsules as an Analgesic for Intraoperative and Post- Endodontic Pain Management in Mandibular Molars With Symptomatic Irreversible Pulpitis A Randomized Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the study is to evaluate the analgesic effect of ginger powder capsules compared to placebo on intra-operative and post-operative pain of single-visit endodontic treatment of mandibular molars with symptomatic irreversible pulpitis
Detailed Description:
The pharmacological pain management usually includes administration of systemic analgesics anti-inflammatory drugs or antibiotics drugs The inhibition of the inflammatory process is one of the methods to reduce or prevent pain during and after treatment
Ginger has a lengthy history of use as a herbal medicine Ginger has been used in traditional Chinese and Indian medicine to treat a variety of diseases including arthritis stomachaches diarrhea nausea asthma and respiratory problems It was discovered that ginger also contains substances that prevent PG production This discovery gave its anti-inflammatory benefits a solid scientific justification Following research it was discovered that some of the components of ginger share pharmacological traits with a novel family of dual-acting NSAIDs These substances have significantly fewer adverse effects than traditional NSAIDs and can inhibit arachidonic acid metabolism via both the cyclooxygenase COX and lipoxygenase LOX pathways
Various animal studies have shown that taking dried ginger or ginger extract orally can decrease acute inflammation Numerous clinical studies back up the effectiveness of ginger in treating osteoarthritis and in some instances a noticeable decrease in knee pain has been reported In some of these studies it was discovered that ginger even when used for extended amounts of time significantly reduced pain and swelling in patients with osteoarthritis rheumatoid arthritis and muscular pain
There have been no studies done to evaluate the impact of ginger powder on intra and post-endodontic pain In order to find the effects of ginger powder capsules on pain after endodontic treatment the current study was performed
Ginger has a lengthy history of use as a herbal medicine Ginger has been used in traditional Chinese and Indian medicine to treat a variety of diseases including arthritis stomachaches diarrhea nausea asthma and respiratory problems It was discovered that ginger also contains substances that prevent PG production This discovery gave its anti-inflammatory benefits a solid scientific justification Following research it was discovered that some of the components of ginger share pharmacological traits with a novel family of dual-acting NSAIDs These substances have significantly fewer adverse effects than traditional NSAIDs and can inhibit arachidonic acid metabolism via both the cyclooxygenase COX and lipoxygenase LOX pathways
Various animal studies have shown that taking dried ginger or ginger extract orally can decrease acute inflammation Numerous clinical studies back up the effectiveness of ginger in treating osteoarthritis and in some instances a noticeable decrease in knee pain has been reported In some of these studies it was discovered that ginger even when used for extended amounts of time significantly reduced pain and swelling in patients with osteoarthritis rheumatoid arthritis and muscular pain
There have been no studies done to evaluate the impact of ginger powder on intra and post-endodontic pain In order to find the effects of ginger powder capsules on pain after endodontic treatment the current study was performed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None