Ignite Creation Date:
2024-06-16 @ 11:49 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06432530
Status:
COMPLETED
Last Update Posted:
2024-05-29
First Post:
2024-05-17
Brief Title:
Can Hematological Inflammatory Indexes be Used to Differentiate Type 1 Modic Changes From Brucella Spondylodiscitis
Sponsor:
Yuzuncu Yıl University
Organization:
Yuzuncu Yıl University
Study Overview
Official Title:
Can Hematological Inflammatory Indexes be Used to Differentiate Type 1 Modic Changes From Brucella Spondylodiscitis
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hematological inflammatory indices Table 2 are currently very popular and have diagnostic prognostic and predictive roles in various diseases Considering their promising roles we hypothesized that hematological inflammatory indices may have a distinctive value between brucella spondylodiscitis and type 1 Modic Changes MCs If the hypothesis is valid early diagnosis-differential diagnosis-treatment processes may become easier and more successful Given that hematological inflammatory indices are faster practical simpler inexpensive and easily accessible indicators they may be more appropriate tools in differentiation between brucella spondylodiscitis and type 1 MCs
Detailed Description:
This is a retrospective comparative study focusing to distinguish between brucella spondylodiscitis and type 1 MCs considering hematological inflammatory indexes Patients data were obtained from Hospital Information Systems between 2020 to 2024 A total of 35 patients with brucella spondylodiscitis and 37 type 1 MCs were enrolled in the study Diagnoses of brucella spondylodiscitis and type 1 MCs were supported by microbiological serological and radiological diagnostic tools Patients hematological parameters were recorded and hematological inflammatory indexes NLR MLR PLR NLPR SII SIRI AISI were derived from baseline CBC tests
Based on the diagnostic tools and criteria121421 cases diagnosed with lumbar brucella spondylodiscitis or lumbar type 1 MCs in the past 5 years and who had simultaneously lumbar MRI Complete Blood Count CBC test C-reactive protein CRP and erythrocyte sedimentation rate ESR results and aged 18-65 years were selected to yield a study population On the other hand cases with inadequate data aged 18 or 64 years other infectious spondylodiscitis types than brucella other MCs types than type 1 and other non-infectious conditions such as rheumatic spondylodiscitis ankylosing spondylitis or Andersson lesion were excluded from the study Also previous or recurrent brucella spondylodiscitis involved other spinal levels than the lumbar spine were exclusion causes
The two groups were statistically assessed and compared for baseline features such as age gender symptom duration CRP ESR CBC values and indexes derived from the CBC
Based on the diagnostic tools and criteria121421 cases diagnosed with lumbar brucella spondylodiscitis or lumbar type 1 MCs in the past 5 years and who had simultaneously lumbar MRI Complete Blood Count CBC test C-reactive protein CRP and erythrocyte sedimentation rate ESR results and aged 18-65 years were selected to yield a study population On the other hand cases with inadequate data aged 18 or 64 years other infectious spondylodiscitis types than brucella other MCs types than type 1 and other non-infectious conditions such as rheumatic spondylodiscitis ankylosing spondylitis or Andersson lesion were excluded from the study Also previous or recurrent brucella spondylodiscitis involved other spinal levels than the lumbar spine were exclusion causes
The two groups were statistically assessed and compared for baseline features such as age gender symptom duration CRP ESR CBC values and indexes derived from the CBC
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None