Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06421987
Status:
RECRUITING
Last Update Posted:
2024-07-01
First Post:
2024-05-01
Brief Title:
Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors
Sponsor:
St Jude Childrens Research Hospital
Organization:
St Jude Childrens Research Hospital
Study Overview
Official Title:
Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
SURVIVORS
Study participants are being asked to take part in this research study called HODNIRS because the participant is a survivor of Hodgkin Lymphoma HL treated with chest radiation and bleomycin at St Jude Childrens Research Hospital The study is being done to help investigators understand the link between long term effects of chest radiation and bleomycin for HL and brain function in survivors
Primary Objective To evaluate dynamic changes in CBF and oxygenation during exercise with Near Infrared Spectroscopy NIRS in HL survivors and non-cancer controls matched for age sex race and ethnicity
Secondary Objectives To examine the degree of CO2 clearance DLCOETCO2 during rest and exercise in Hodgkin Lymphoma HL survivors compared to non-cancer controls matched for age sex race and ethnicity
CONTROLS
Volunteers are being asked to take part in this research study because they are non-first degree relative or friend of someone who received treatment for a childhood cancer or similar illness at St Jude Childrens Research Hospital or are an employeeaffiliate of St Jude Childrens Research Hospital and have agreed to be a St Jude Life Cohort Study SJLIFE community control
Study participants are being asked to take part in this research study called HODNIRS because the participant is a survivor of Hodgkin Lymphoma HL treated with chest radiation and bleomycin at St Jude Childrens Research Hospital The study is being done to help investigators understand the link between long term effects of chest radiation and bleomycin for HL and brain function in survivors
Primary Objective To evaluate dynamic changes in CBF and oxygenation during exercise with Near Infrared Spectroscopy NIRS in HL survivors and non-cancer controls matched for age sex race and ethnicity
Secondary Objectives To examine the degree of CO2 clearance DLCOETCO2 during rest and exercise in Hodgkin Lymphoma HL survivors compared to non-cancer controls matched for age sex race and ethnicity
CONTROLS
Volunteers are being asked to take part in this research study because they are non-first degree relative or friend of someone who received treatment for a childhood cancer or similar illness at St Jude Childrens Research Hospital or are an employeeaffiliate of St Jude Childrens Research Hospital and have agreed to be a St Jude Life Cohort Study SJLIFE community control
Detailed Description:
NIRS is a portable non-invasive brain imaging device that uses low levels of non-ionizing light to record variations in blood flow in the brain The NIRS is wearable and can read blood flow to the brain during physical activity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NCI-2024-03932 | REGISTRY | None | None |