Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06420752
Status:
RECRUITING
Last Update Posted:
2024-05-20
First Post:
2024-05-14
Brief Title:
Passive Stretching in Peripheral Arterial Disease Patients
Sponsor:
University of Wisconsin La Crosse
Organization:
University of Wisconsin La Crosse
Study Overview
Official Title:
Passive Stretching and Dietary Nitrate Rescue Functional Capacity in Peripheral Arterial Disease
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Peripheral artery disease PAD leads to higher mortality rates and strains healthcare systems due to increased costs It causes leg pain during walking due to reduced blood flow Nitric oxide NO deficiency contributes to vascular issues in PAD with few effective treatments available Passive calf muscle stretching boosts NO levels vascular health and walking ability in PAD patients However the inflammatory processes underlying these improvements are unclear This study aims to track inflammatory markers and cardiovascular changes during 12 weeks of passive stretching Additionally combining stretching with dietary nitrate could further enhance walking capacity by reducing reactive oxygen species The study will monitor inflammation vascular function and oxidative capacity to understand the effects on functional ability in PAD patients This research is crucial for improving physical function and addressing exercise intolerance in PAD
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None