Ignite Creation Date:
2024-06-16 @ 11:48 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06428227
Status:
COMPLETED
Last Update Posted:
2024-05-29
First Post:
2024-05-20
Brief Title:
Exercise Capacity and Fatigue in Heart Failure Patients With and Without Inspiratory Muscle Weakness
Sponsor:
Gazi University
Organization:
Gazi University
Study Overview
Official Title:
A Comparison of Exercise Capacity Respiratory Functions and Quality of Life in Heart Failure Patients With and Without Inspiratory Muscle Weakness and Healthy Controls
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In patients with heart failure diaphragm dysfunction contributes to decreased quality of life while simultaneously increasing morbidity and mortality Inspiratory muscle weakness is observed in 30-50 of patients with the severity of weakness increasing as the disease progresses Patients exhibit reduced exercise capacity peripheral and respiratory muscle strength decreased respiratory function increased dyspnea fatigue and worsened quality of life However it is unclear how these parameters will change in patients with inspiratory muscle weakness Therefore the study aimed to compare functional exercise capacity pulmonary function peripheral muscle strength dyspnea fatigue quality of life and physical activity level in heart failure patients with and without inspiratory muscle weakness and healthy controls
Detailed Description:
It is believed that respiratory muscle abnormalities develop earlier and more extensively than extremity muscle abnormalities in heart failure Diaphragm dysfunction contributes to decreased quality of life while simultaneously increasing morbidity and mortality Inspiratory muscle weakness is observed in 30-50 of patients with the severity of weakness increasing as the disease progresses Heart failure patients exhibit increased airway resistance and ventilatory response during exercise Fatigue and dyspnea are common symptoms associated with exercise intolerance and decreased quality of life in heart failure patientsThere is no study in the literature comparing functional exercise capacity pulmonary function peripheral muscle strength dyspnea fatigue quality of life and physical activity level in heart failure patients with and without inspiratory muscle weakness IMW The aim of the study was to compare functional exercise capacity pulmonary function peripheral muscle strength dyspnea fatigue quality of life and physical activity level in heart failure patients with and without IMW and healthy controls
The study was planned as a cross-sectional retrospective Heart failure patient were divided into IMW group or not IMW group due to their MIP values Also healthy controls who were matched for age-gender were included
The study was planned as a cross-sectional retrospective Heart failure patient were divided into IMW group or not IMW group due to their MIP values Also healthy controls who were matched for age-gender were included
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None