Ignite Creation Date:
2024-06-16 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06427187
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-23
First Post:
2024-05-18
Brief Title:
Mechanical Thrombectomy of Acute Ischemic Stroke Anterior Circulation Distal Vessel Occlusion
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Outcomes of Mechanical Thrombectomy of Acute Ischemic Stroke Anterior Circulation Distal Vessel Occlusion
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Ischemic stroke continues to be of the leading causes of disability and death Distal vessel occlusion one of most presenting and disabling varieties of ischemic stroke Distal vessel occlusion stroke is a type of ischemic stroke that affects the small arteries in the brain usually beyond the M2 segment of the middle cerebral artery These strokes can cause various neurological symptoms depending on the location and size of the occluded vessel and the extent of the brain tissue damage
Detailed Description:
DMVOs are defined by the Distal Thrombectomy Summit Group consensus statement as thromboembolic occlusion of the anterior cerebral artery M2-M4 middle cerebral artery MCA posterior cerebral artery PCA posterior inferior cerebellar artery anterior inferior cerebellar artery or superior cerebellar artery It is estimated that 25-40 of all AIS is due to DMVOThough distal vessel occlusion associated with poor disabling comorbiditiesWith different aetiology weather primary Embolic from heart carotid or aortathrombotic atherosclerotic hypertension or Diabetes smoking hyperlipidaemia or Secondary distal vessel occlusion that occurs as a complication of a proximal large vessel occlusion either spontaneously or after treatment with intravenous thrombolysis or endovascular thrombectomy This can be due to thrombus fragmentation and migration or incomplete reperfusion of the affected vascular territory Endovascular thrombectomy is well established as a highly effective treatment for acute ischemic stroke AIS due to proximal large vessel occlusions PLVOs Recent advances in stent retriever and aspiration catheter technology are more promising results to reach more distal vessels with a good outcome However MT in M2 emerging with different technique using stent Retriever or aspiration or both nowadays evidence of other MT in distal vessel occlusion is poor
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None