Ignite Creation Date:
2024-06-16 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06425354
Status:
RECRUITING
Last Update Posted:
2024-05-22
First Post:
2024-05-17
Brief Title:
Use of Mechanical Power as a Predictor of Increased Serum and Pulmonary Proinflammatory Cytokine Concentrations in Patients With Acute Hypoxemic Respiratory Failure A Prospective Observational Study
Sponsor:
University of Roma La Sapienza
Organization:
University of Roma La Sapienza
Study Overview
Official Title:
Use of Mechanical Power as a Predictor of Increased Serum and Pulmonary Proinflammatory Cytokine Concentrations in Patients With Acute Hypoxemic Respiratory Failure A Prospective Observational Study
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to report the proportion of patients with acute hypoxemic respiratory failyre AHRF undergoing mechanical ventilation who exceed 17 Jmin of mechanical power MP and the difference in terms of proinflammatory cytokine concentration in blood samples and bronchoalveolar lavage
The main questions it aims to answer are
1 Which is the proportion of patients who exceed 17 Jmin of mechanical power MP during the first 72 hours of mechanical ventilation
2 Is there a difference in terms of cytokine concentration in patients undergoing mechanical power 17 Jmin compared to 17 Jmin
Patients will be divided into two groups based on respiratory mechanics measurements low MP group average MP 17 Jmin and high MP group average MP 17 Jmin The researchers will collect blood and BAL samples and perform cytokine assays
The main questions it aims to answer are
1 Which is the proportion of patients who exceed 17 Jmin of mechanical power MP during the first 72 hours of mechanical ventilation
2 Is there a difference in terms of cytokine concentration in patients undergoing mechanical power 17 Jmin compared to 17 Jmin
Patients will be divided into two groups based on respiratory mechanics measurements low MP group average MP 17 Jmin and high MP group average MP 17 Jmin The researchers will collect blood and BAL samples and perform cytokine assays
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None