Ignite Creation Date:
2024-06-16 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06421805
Status:
RECRUITING
Last Update Posted:
2024-05-20
First Post:
2024-04-20
Brief Title:
Establishing Prospective Mediastinal Tumor Database of PUMCH
Sponsor:
Peking Union Medical College Hospital
Organization:
Peking Union Medical College Hospital
Study Overview
Official Title:
A Single-center Prospective and Observational Study on Population Characteristics Pathological Features and Prognostic Factors of Patients With Mediastinal Tumor Establishing Mediastinal Tumor Database of PUMCH
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MTDPUMCH
Brief Summary:
This study aims to prospectively document the population characteristics imaging findings pathological features prognostic factors etc of patients with mediastinal tumors Clinical information will be structured and processed and it is recommended to establish a mediastinal tumors database at Peking Union Medical College Hospital The goal is to provide support for the quality of diagnosis and treatment clinical protocols and medical decision-making related to mediastinal tumors
Detailed Description:
Mediastinal tumors encompass a variety of tumors originating in the mediastinum comprising both benign and malignant tumors those invading mediastinal structures during disease progression or metastases from malignant tumors originating elsewhere in the body Based on their relationship with the pericardium mediastinal tumors can be categorized into anterior mediastinal tumors commonly including thymomas retrosternal goiters teratomas and germ cell tumors middle mediastinal tumors which often include bronchogenic cysts lymphomas malignant lymphomas pericardial cysts lipomas and esophageal cysts and posterior mediastinal tumors where neurogenic tumors and neurofibromas are prevalent Mediastinal tumors are relatively rare compared to other solid tumors and exhibit complex pathological types Consequently conducting prospective randomized controlled clinical trials is challenging and the significant treatment disparities among different types of mediastinal tumors affect patient survival outcomes Clinicians often have limited understanding of some complex mediastinal tumors due to the lack of quality and reliable diagnostic and treatment standards or survival data Therefore establishing a specialized database for mediastinal tumor research holds great practical significance for the effective development of clinical practice
Tumor registration databases in North America and Europe have been established earlier with wide coverage and relatively mature development For example the National Cancer Database NCDB in the United States is the largest tumor registration database globally with over 1500 hospitals reporting tumor data to it covering approximately 70 of newly diagnosed cancer cases The Surveillance Epidemiology and End Results SEER database is a public health database based on tumor populations in some states and counties in the United States 17 regional registration centers It has been registering data since 1973 covering tumor monitoring epidemiology and prognosis information Both databases have high coverage and reasonable registration and verification systems providing a wealth of high-level evidence for the formulation of tumor prevention and control strategies
In China the development in this field started relatively late To integrate resources deeply explore data information and further improve the diagnosis and treatment level and patient management level of mediastinal tumors in China it is necessary to establish a scientifically standardized specialized mediastinal tumor database
Tumor registration databases in North America and Europe have been established earlier with wide coverage and relatively mature development For example the National Cancer Database NCDB in the United States is the largest tumor registration database globally with over 1500 hospitals reporting tumor data to it covering approximately 70 of newly diagnosed cancer cases The Surveillance Epidemiology and End Results SEER database is a public health database based on tumor populations in some states and counties in the United States 17 regional registration centers It has been registering data since 1973 covering tumor monitoring epidemiology and prognosis information Both databases have high coverage and reasonable registration and verification systems providing a wealth of high-level evidence for the formulation of tumor prevention and control strategies
In China the development in this field started relatively late To integrate resources deeply explore data information and further improve the diagnosis and treatment level and patient management level of mediastinal tumors in China it is necessary to establish a scientifically standardized specialized mediastinal tumor database
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None