Ignite Creation Date:
2024-06-16 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06427512
Status:
WITHDRAWN
Last Update Posted:
2024-05-24
First Post:
2022-02-01
Brief Title:
Mechanisms Underlying Cardiovascular Consequences Associated With COVID-19 and Long COVID
Sponsor:
Columbia University
Organization:
Columbia University
Study Overview
Official Title:
Mechanisms Underlying Cardiovascular Consequences Associated With COVID-19 and Long COVID - Characterizing Long COVID Phenotypes Using Physiological and Molecular Studies
Status:
WITHDRAWN
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Funding not available
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
AIM 1 Characterize cardiovascular phenotypes of long COVID by cardiopulmonary meta-bolic and cardiac mechanicalphysiological responses to exercise and microvascular vasomotor function
AIM 2 Identify intercellular signaling between immune cells and cardiac cells associated with microvascular phenotypes of long COVID
AIM 2 Identify intercellular signaling between immune cells and cardiac cells associated with microvascular phenotypes of long COVID
Detailed Description:
As many as 40-60 of patients who recovered from mild or moderate acute COVID have reported what is now called long COVID - multiple persistent or recurrent symptoms lasting 6-9 months or longer following initial illness1-4 Fatigue dyspnea and chest pain are the most common symptoms Others include palpitations lightheadedness and syncope All these cardiovascular symptoms can be debilitating resulting in worse quality of life and morbidity5 6 Treatment options are limited
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None