Ignite Creation Date:
2024-05-19 @ 5:35 PM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06415682
Status:
RECRUITING
Last Update Posted:
2024-05-28
First Post:
2024-05-05
Brief Title:
The Efficacy and Mechanism of SMAM1 Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
Sponsor:
The First Affiliated Hospital with Nanjing Medical University
Organization:
The First Affiliated Hospital with Nanjing Medical University
Study Overview
Official Title:
The Efficacy and Mechanism of SMAM1 Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a double-blinded randomized study examining the efficacy of the double-site M1SMA repetitive transcranial magnetic stimulation on Freezing of Gait FOG in patients with Parkinsons disease The investigators hypothesize that treatment using magnetic stimulation on double site including M1-LL and SMA will improve FOG and gait symptoms in patients with Parkinsons disease
Detailed Description:
Patients in the double-site group underwent ten sessions of double-site high frequency rTMS over the bilateral primary motor cortex of the lower leg and supplementary motor area whereas patients in the single-site group underwent ten sessions of single-site active magnetic stimulation with high frequency rTMS over the bilateral primary motor cortex of the lower leg In addition patients in the sham group underwent 10 sessions of sham rTMS on bilateral primary motor cortex of the lower leg Assessments of FOG severity gait motor symptoms excitability of cortex motor using transcranial magnetic stimulation plasma indicators and multimodal magnetic resonance were performed three times at baseline one day post intervention one month post intervention
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None