Ignite Creation Date:
2024-05-19 @ 5:34 PM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06411236
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-13
First Post:
2024-05-08
Brief Title:
Functional Response Characteristics of Brain Under Swallowing Task Paradigm
Sponsor:
Ruyao Liu
Organization:
The First Affiliated Hospital of Zhengzhou University
Study Overview
Official Title:
Functional Response Characteristics of Brain Under Swallowing Task Paradigm Based on Functional Near-infrared Spectroscopy
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Functional near-infrared spectroscopy was used to investigate the cortical activation patterns and lateralization during swallowing tasks in 15 healthy middle-aged and elderly people and 15 healthy young people It provides a theoretical basis for the study of swallowing function and a new idea for the treatment of patients with swallowing disorders
Detailed Description:
Swallowing is coordinated by hyoid muscle group pharyngeal muscle and upper esophageal muscle as well as the regulation of swallowing related functional brain area Dysphagia refers to the inability to safely and effectively transport food from the mouth to the stomach to obtain adequate nutrition and water resulting in eating difficulties Studies have shown that swallowing disorders are mainly caused by stroke brain trauma neurodegenerative diseases Alzheimers disease Parkinsons disease multiple sclerosis and amyotrophic lateral sclerosis and head and neck cancers oral tumors nasopharyngeal and laryngeal cancers Moreover the prevalence of dysphagia increases with age Patients with dysphagia often have many complications which may lead to dehydration malnutrition aspiration pneumonia etc which greatly delays the recovery process of patients and reduces the quality of life of patients Studies have shown that the swallowing network includes multiple brain regions including the primary somatosensory cortex primary motor cortex bilateral premotor and auxiliary motor cortex cingulate cortex prefrontal temporal precuneus subparietal lobule cerebellum and cerebellum
At present there are some functional near-infrared spectroscopy studies on the swallowing function of healthy people which mainly focus on healthy young subjects and studies show that the incidence of swallowing disorders increases with age the incidence of swallowing disorders in people over 50 years old is 55 8 and swallowing disorders are mainly concentrated in middle-aged and elderly people At present there are no studies on swallowing function in middle-aged and elderly healthy subjects with functional near-infrared spectroscopy The purpose of this study is to explore and compare the cortical activation patterns and lateralization in the swallowing task of healthy middle-aged and elderly people and young people by using functional near-infrared spectroscopy providing a theoretical basis for the exploration of swallowing function and further providing new ideas for the treatment of patients with swallowing disorders
At present there are some functional near-infrared spectroscopy studies on the swallowing function of healthy people which mainly focus on healthy young subjects and studies show that the incidence of swallowing disorders increases with age the incidence of swallowing disorders in people over 50 years old is 55 8 and swallowing disorders are mainly concentrated in middle-aged and elderly people At present there are no studies on swallowing function in middle-aged and elderly healthy subjects with functional near-infrared spectroscopy The purpose of this study is to explore and compare the cortical activation patterns and lateralization in the swallowing task of healthy middle-aged and elderly people and young people by using functional near-infrared spectroscopy providing a theoretical basis for the exploration of swallowing function and further providing new ideas for the treatment of patients with swallowing disorders
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None