Ignite Creation Date:
2024-05-19 @ 5:33 PM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06410391
Status:
RECRUITING
Last Update Posted:
2024-06-18
First Post:
2024-05-03
Brief Title:
Fetal Brain Ultrasound
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Fetal Brain Sonographic Measurements and Normograms in Healthy Fetuses During Second and Third Trimesters
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of our study is to determine the range of frontal horn sizes both upside and downside in healthy fetuses over gestation and to determine how far FHs are from the midline Also to determine the range of cavum septi pellucidi and Corpus callosum sizes Also to determine whether the maternal body mass index BMI affects rates of visualized and non-visualized CSP and CC
Detailed Description:
Fetal central nervous system CNS abnormalities are among the most commonly encountered congenital abnormalities Many different methods can be used to obtain prenatal diagnoses including ultrasound US which is one of the most commonly used methods Neonatal survival rates have increased over the last decades leading to increased number of infants with adverse neurodevelopmental outcomes including cognitive motor impairments and behavioral and learning difficulties later in life Recent studies demonstrated that signs of abnormal neurological development are already present at birth
Frontal horns FHs are the most anterior portions of the lateral ventricles on each side the cavum septi pellucidi CSP In accordance with practice parameters released as early as 1985 by the American Institute of Ultrasound in Medicine American College of Obstetrics and Gynecology and Society of Radiologists in Ultrasound the CSP is examined in screening fetal ultrasound US examinations in the biparietal diameter view Frontal horns FH are also visualized in the same plane Abnormal morphologic characteristics of the FHs such as enlargement squaring spearing and splaying may have an association with congenital intracranial anomalies such as holoprosencephaly schizencephaly and agenesis of the corpus callosum
The corpus callosum CC is the largest interhemispheric white matter commissure of the human brain It is a sensitive indicator of normal brain development and maturation
Frontal horns FHs are the most anterior portions of the lateral ventricles on each side the cavum septi pellucidi CSP In accordance with practice parameters released as early as 1985 by the American Institute of Ultrasound in Medicine American College of Obstetrics and Gynecology and Society of Radiologists in Ultrasound the CSP is examined in screening fetal ultrasound US examinations in the biparietal diameter view Frontal horns FH are also visualized in the same plane Abnormal morphologic characteristics of the FHs such as enlargement squaring spearing and splaying may have an association with congenital intracranial anomalies such as holoprosencephaly schizencephaly and agenesis of the corpus callosum
The corpus callosum CC is the largest interhemispheric white matter commissure of the human brain It is a sensitive indicator of normal brain development and maturation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None