Ignite Creation Date:
2024-05-19 @ 5:33 PM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06410417
Status:
RECRUITING
Last Update Posted:
2024-05-13
First Post:
2024-04-25
Brief Title:
Ejaculation Abstinence Time and Assisted Reproductive Technology Outcomes
Sponsor:
The First Hospital of Jilin University
Organization:
The First Hospital of Jilin University
Study Overview
Official Title:
The Effect of Reducing Ejaculation Abstinence Time on Assisted Reproductive Technology Outcomes a Prospective Randomized Controlled Study
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to learn if reducing the ejaculation abstinence time can improve the outcome of assisted reproductive technology The main questions it aims to answer are
Does reducing the duration of ejaculation abstinence improve the clinical pregnancy rate for in vitro fertilization and intracytoplasmic sperm injection Does reducing the duration of ejaculation abstinence improve embryo quality in in vitro fertilization and intracytoplasmic sperm injection Does reducing the duration of ejaculation abstinence affect pregnancy loss and live birth rates in in vitro fertilization and intracytoplasmic sperm injection
Researchers will compare less than 48 hours of abstinence time to more than 48 hours to see if less than 48 hours of abstinence time improved in vitro fertilization outcomes
Participants will
Control group abstinence for 3-7 days
The experimental group ejaculated once on human chorionic gonadotropin trigger day
Follow up their in vitro fertilization outcomes
Does reducing the duration of ejaculation abstinence improve the clinical pregnancy rate for in vitro fertilization and intracytoplasmic sperm injection Does reducing the duration of ejaculation abstinence improve embryo quality in in vitro fertilization and intracytoplasmic sperm injection Does reducing the duration of ejaculation abstinence affect pregnancy loss and live birth rates in in vitro fertilization and intracytoplasmic sperm injection
Researchers will compare less than 48 hours of abstinence time to more than 48 hours to see if less than 48 hours of abstinence time improved in vitro fertilization outcomes
Participants will
Control group abstinence for 3-7 days
The experimental group ejaculated once on human chorionic gonadotropin trigger day
Follow up their in vitro fertilization outcomes
Detailed Description:
The goal of this clinical trial is to learn if reducing the ejaculation abstinence time can improve the outcome of assisted reproductive technology
Group A Experimental group ejaculation once within 48 hours before the day of egg retrieval
Group B Control group ejaculation once within 4-7 days before the day of egg retrieval
There is currently no clear abstinence period for in vitro fertilization and the usual practice is to refer to the World Health Organization standard for semen testing abstinence period of 2-7 daysGroup A ejaculated once 48 hours before egg retrievalGroup B was the control group and ejaculation was performed according to the conventional protocolMost IVF intervals from ovulation initiation to human chorionic gonadotropin trigger day range from 8-11 days but the fixed time of egg retrieval is 34-37 hours after the trigger dayTherefore when determining the human chorionic gonadotropin time it is less than 48 hours before egg retrievalIn the experimental group male ejaculates once on the trigger day and can be ejaculated on the second day if ejaculates fail
Follow up their in vitro fertilization outcomes
Group A Experimental group ejaculation once within 48 hours before the day of egg retrieval
Group B Control group ejaculation once within 4-7 days before the day of egg retrieval
There is currently no clear abstinence period for in vitro fertilization and the usual practice is to refer to the World Health Organization standard for semen testing abstinence period of 2-7 daysGroup A ejaculated once 48 hours before egg retrievalGroup B was the control group and ejaculation was performed according to the conventional protocolMost IVF intervals from ovulation initiation to human chorionic gonadotropin trigger day range from 8-11 days but the fixed time of egg retrieval is 34-37 hours after the trigger dayTherefore when determining the human chorionic gonadotropin time it is less than 48 hours before egg retrievalIn the experimental group male ejaculates once on the trigger day and can be ejaculated on the second day if ejaculates fail
Follow up their in vitro fertilization outcomes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None