Ignite Creation Date:
2024-05-11 @ 8:31 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06406647
Status:
RECRUITING
Last Update Posted:
2024-06-05
First Post:
2024-05-06
Brief Title:
Rectroclavicular Block in Orthopedic Surgey
Sponsor:
New Valley University
Organization:
New Valley University
Study Overview
Official Title:
Adding Ketamine as Adjuvant in Retroclavicular Block in Upper Limb Orthopedic Surgey
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The ultrasound-guided retroclavicular approach to the infraclavicular region RAPTIR brachial plexus block has gained popularity as a relatively easy-to-perform nerve block that provides reliable and dense anesthesia to the upper extremity with a single injection The block has been well described in the anesthesia community since it was first introduced by Hebbard and Royse in 2007 In 2017 Luftig first described the blocks use in the ED setting for a variety of indications This nerve block has classically been described to provide extensive anesthesia for procedures distal to the shoulder such as elbow dislocations distal radius fractures and surgical procedures
Detailed Description:
Ultrasound-guided regional anesthesia of the infraclavicular brachial plexus offers dense anesthesia of the distal upper extremity The Retro clavicular Approach to The Infraclavicular Region RAPTIR is an ultrasound-guided brachial plexus block that has only recently been described in both anesthesia and emergency literature
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia It is also used as a treatment for depression a pain management tool and as a recreational drug Ketamine is a novel compound that was derived from phencyclidine in 1962 in pursuit of a safer anesthetic with fewer hallucinogenic effects
At anesthetic doses ketamine induces a state of dissociative anesthesia a trance-like state providing pain relief sedation and amnesia The distinguishing features of ketamine as anesthesia are preserved breathing and airway reflexes stimulated heart function with increased blood pressure and moderate bronchodilation At lower sub-anesthetic doses ketamine is a promising agent for pain and treatment-resistant depression As with many antidepressants the results of a single administration of ketamine wane with time The long-term effects of repeated use are largely unknown and are an area of active investigation
Liver and urinary toxicity have been reported among regular users of high doses of ketamine for recreational purposes Ketamine is an NMDA receptor pore blocker accounting for most of its actions but not the antidepressant effect the mechanism of which is a matter of research and debate
Ketamine was first synthesized in 1962 and approved for use in the United States in 1970 It has been regularly used in veterinary medicine and was extensively used for surgical anesthesia in the Vietnam War Along with other psychotropic drugs it is on the World Health Organizations List of Essential Medicines It is available as a generic medication When used as a recreational drug it is found both in powder and liquid form and is often referred to as Special K for its hallucinogenic and dissociative effects
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia It is also used as a treatment for depression a pain management tool and as a recreational drug Ketamine is a novel compound that was derived from phencyclidine in 1962 in pursuit of a safer anesthetic with fewer hallucinogenic effects
At anesthetic doses ketamine induces a state of dissociative anesthesia a trance-like state providing pain relief sedation and amnesia The distinguishing features of ketamine as anesthesia are preserved breathing and airway reflexes stimulated heart function with increased blood pressure and moderate bronchodilation At lower sub-anesthetic doses ketamine is a promising agent for pain and treatment-resistant depression As with many antidepressants the results of a single administration of ketamine wane with time The long-term effects of repeated use are largely unknown and are an area of active investigation
Liver and urinary toxicity have been reported among regular users of high doses of ketamine for recreational purposes Ketamine is an NMDA receptor pore blocker accounting for most of its actions but not the antidepressant effect the mechanism of which is a matter of research and debate
Ketamine was first synthesized in 1962 and approved for use in the United States in 1970 It has been regularly used in veterinary medicine and was extensively used for surgical anesthesia in the Vietnam War Along with other psychotropic drugs it is on the World Health Organizations List of Essential Medicines It is available as a generic medication When used as a recreational drug it is found both in powder and liquid form and is often referred to as Special K for its hallucinogenic and dissociative effects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None