Ignite Creation Date:
2024-05-11 @ 8:31 AM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06402890
Status:
COMPLETED
Last Update Posted:
2024-05-07
First Post:
2024-04-17
Brief Title:
Resistance Training and Hydrolyzed Collagen Supplementation in Middle-aged Adults
Sponsor:
Liverpool John Moores University
Organization:
Liverpool John Moores University
Study Overview
Official Title:
The Effect of Vitamin C-enriched Collagen Combined With Resistance Training on Muscle-tendon Unit Properties in Middle-aged Men and Women
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this clinical trial is to investigate the longitudinal effects of hydrolyzed collagen ingestion combined with resistance training on muscle-tendon unit structure and function in middle-aged males and females
The main research questions this clinical trial aims to answer are
1 Does resistance training with hydrolyzed collagen ingestion lead to greater changes in tendon properties than resistance training alone in middle-aged health men and women
2 Does resistance training with hydrolyzed collagen ingestion lead to greater changes in muscle size than resistance training alone
3 Does resistance training with hydrolyzed collagen lead to greater increases in strength and power compared to resistance training alone in middle-aged healthy men and women
Participants will be randomly assigned to collagen or placebo groups Participants will perform 24 sessions of high intensity resistance training across 12-weeks Alongside each training session participants will consume a beverage containing hydrolyzed collagen or maltodextrin with both beverages containing vitamin C
Researchers will compare the collagen and placebo groups to see if there would be beneficial effects on changes in muscle and tendon that are greater than resistance training alone To achieve this an dynamometry will be used to assess lower limb strength and ultrasound will be used to measure the morphological mechanical and material properties of the patellar tendon as well the size and architecture of the vastus lateralis muscle
The main research questions this clinical trial aims to answer are
1 Does resistance training with hydrolyzed collagen ingestion lead to greater changes in tendon properties than resistance training alone in middle-aged health men and women
2 Does resistance training with hydrolyzed collagen ingestion lead to greater changes in muscle size than resistance training alone
3 Does resistance training with hydrolyzed collagen lead to greater increases in strength and power compared to resistance training alone in middle-aged healthy men and women
Participants will be randomly assigned to collagen or placebo groups Participants will perform 24 sessions of high intensity resistance training across 12-weeks Alongside each training session participants will consume a beverage containing hydrolyzed collagen or maltodextrin with both beverages containing vitamin C
Researchers will compare the collagen and placebo groups to see if there would be beneficial effects on changes in muscle and tendon that are greater than resistance training alone To achieve this an dynamometry will be used to assess lower limb strength and ultrasound will be used to measure the morphological mechanical and material properties of the patellar tendon as well the size and architecture of the vastus lateralis muscle
Detailed Description:
Healthy active middle-aged men and women will ingest a beverage containing 30 g of hydrolyzed collagen with 50 mg of vitamin C or a calorie matched beverage maltodextrin also with 50 mg of vitamin C combined with high-volume high-intensity resistance training for the lower body on 2 - 3 occasions per week for 8-12 weeks
The aim of this study was to investigate the effect of combining hydrolyzed collagen with resistance training in middle-aged men and womenIf supplementation with hydrolyzed collagen leads to a greater change in tendon size stiffness and Youngs modulus than resistance training alone this will allow us to recommend this type of intervention to young athletes seeking to improve tendon health andor athletic performance This is the first study to investigate the combination of hydrolyzed collage supplementation with resistance training in middle-aged men and women If supplementation with hydrolyzed leads to greater improvements in tendon size stiffness strength andor power this will allow us to recommend this type of intervention to middle-aged athletestrainees seeking to improve tendon health reduce injury risk or enhance athletic performance
The experimental design of both arms will be the same however Arm 1 will be health middle-aged male participants and Arm 2 will be health middle-aged female participants
The aim of this study was to investigate the effect of combining hydrolyzed collagen with resistance training in middle-aged men and womenIf supplementation with hydrolyzed collagen leads to a greater change in tendon size stiffness and Youngs modulus than resistance training alone this will allow us to recommend this type of intervention to young athletes seeking to improve tendon health andor athletic performance This is the first study to investigate the combination of hydrolyzed collage supplementation with resistance training in middle-aged men and women If supplementation with hydrolyzed leads to greater improvements in tendon size stiffness strength andor power this will allow us to recommend this type of intervention to middle-aged athletestrainees seeking to improve tendon health reduce injury risk or enhance athletic performance
The experimental design of both arms will be the same however Arm 1 will be health middle-aged male participants and Arm 2 will be health middle-aged female participants
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None