Ignite Creation Date:
2024-05-11 @ 8:31 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06409585
Status:
RECRUITING
Last Update Posted:
2024-05-10
First Post:
2024-05-07
Brief Title:
Cardiomyopathies and Heart Muscle Diseases Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Sponsor:
University of Edinburgh
Organization:
University of Edinburgh
Study Overview
Official Title:
Cardiomyopathies and Heart Muscle Diseases Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CHIEFTain
Brief Summary:
Heart scarring also known as fibrosis plays a major role in a lot of heart muscle abnormalities These abnormalities of the heart muscle can lead to major issues such as symptoms of heart failure dangerous heart rhythm disturbances and even death However a lot of these conditions are still not fully understood and treatment options are limited We here aim to use a new radioactive dye called 68Ga-FAPI to identify patterns and the activity of heart muscle scarring This radioactive dye is being used in humans particularly in identifying and monitoring cancers and has shown promise in identifying scarring in the heart as well This will help us not only understand the underlying disease process and risk stratify these patients but also potentially help us develop new targeted therapies that can affect heart muscle scarring Participants will undergo a baseline MRI scan using this new dye and a plain MRI scan will repeated 12-18 months after to see if there are any changes in the process
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None