Ignite Creation Date:
2024-05-11 @ 8:31 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06407375
Status:
RECRUITING
Last Update Posted:
2024-05-09
First Post:
2024-05-06
Brief Title:
Assessment of Renal Function by Multiparametric MRI
Sponsor:
University of Zurich
Organization:
University of Zurich
Study Overview
Official Title:
Assessment of Renal Function by Multiparametric MRI
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Metabolic syndrome is a collection of conditions that affect at least three of the following five criteria abdominal obesity high blood pressure high fasting glucose levels high triglyceride levels and low levels of high-density lipoprotein HDL cholesterol Chronic kidney disease CKD is a common complication of metabolic syndrome with an estimated prevalence of 13-40 Early diagnosis of progressive conditions before the onset of reduced glomerular filtration rate GFR or albuminuria may be of clinical benefit but is not possible at present Furthermore the diagnosis and quantification of CKD in the context of metabolic syndrome is challenging due to the lack of reliable diagnostic biomarkers and the current methods may not accurately reflect kidney function in patients with metabolic syndrome Magnetic resonance imaging MRI has been sparsely explored as a potential tool to assess renal perfusion oxygenation and fibrosis Multiparametric MRI mpMRI combines several different imaging techniques to provide a more comprehensive evaluation of tissue structure and function These techniques hold promise for non-invasive assessment of kidney function but their clinical utility is still largely experimental Therefore we aim to conduct an exploratory study to investigate the reliability reproducibility as well as the validity of parameters for kidney function of multiparametric MRI as well as compare these parameters in between healthy patients and patients with metabolic syndrome
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None