Ignite Creation Date:
2024-05-11 @ 8:31 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06404554
Status:
COMPLETED
Last Update Posted:
2024-05-08
First Post:
2024-05-05
Brief Title:
A Prediction Model of Anastomotic Stricture After Rectal Cancer
Sponsor:
Northern Jiangsu Peoples Hospital
Organization:
Northern Jiangsu Peoples Hospital
Study Overview
Official Title:
A Prediction Model of Anastomotic Stricture After Rectal Cancer a Retrospective Cohort Analysis
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Anastomotic stricture significantly impacts patients quality of life and long-term prognosis However current clinical practice lacks accurate tools for predicting anastomotic stricture This study aimed to develop a nomogram to predict anastomotic stricture in patients with rectal cancer who have undergone anterior resection
Methods 1542 eligible patients will be recruited for the study Least absolute shrinkage selection operator Lasso analysis will be used to preliminarily select predictors A prediction model will be constructed using multivariate logistic regression and presented as a nomogram The performance of the nomogram will be evaluated using receiver operating characteristic ROC curves calibration diagrams and decision curve analysis DCA Internal validation will be conducted by assessing the models performance on a validation cohort
Methods 1542 eligible patients will be recruited for the study Least absolute shrinkage selection operator Lasso analysis will be used to preliminarily select predictors A prediction model will be constructed using multivariate logistic regression and presented as a nomogram The performance of the nomogram will be evaluated using receiver operating characteristic ROC curves calibration diagrams and decision curve analysis DCA Internal validation will be conducted by assessing the models performance on a validation cohort
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None