Ignite Creation Date:
2024-05-11 @ 8:30 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06405776
Status:
RECRUITING
Last Update Posted:
2024-05-08
First Post:
2024-05-05
Brief Title:
Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery
Sponsor:
West China Hospital
Organization:
West China Hospital
Study Overview
Official Title:
Effect of Perioperative Continuous Intravenous Infusion of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Cancer Surgery a Prospective Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain long-term quality of life and survival rate in patients undergoing colorectal cancer surgery
Detailed Description:
This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain long-term quality of life and survival rate in patients undergoing colorectal cancer surgery Patients who meet the enrollment criteria will be randomized 11 to the lidocaine group or placebo group In the lidocaine group lidocaine 15mgkgh was continuously infused using ideal body weight during the whole procedure Postoperative analgesia pump with lidocaine lidocaine 50mgkg sufentanil 2ugkg glassetron 12mg diluted to 200ml with saline until 72h after surgery In the placebo group the same volume of normal saline will be administered during anesthesia The postoperative PCIA device will contain sufentanil 2μgkg granisetron 12mg diluted to 200mL in 09 normal saline solution with a total volume of 200mLFollow-up after discharge includes chronic pain the impact of chronic pain on quality of life the relapse-free survival and overall survival from postoperative 3 months to 5 years
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None