Ignite Creation Date:
2024-05-11 @ 8:30 AM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06401122
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-06
First Post:
2024-05-02
Brief Title:
Comparison of Dyslipidemia Among Diabetics Versus Non Diabetics in Haemodialysis Patients
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Comparison of Dyslipidemia Among Diabetics Versus Non Diabetics in Haemodialysis
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
How dyslipidemia common among Diabetic and non- Diabetic Haemodialysis patients
How differ dyslipidemia types among Diabetic and non- Diabetic in Haemodialysis patients Qualitative difference
How differ dyslipidemia types among Diabetic and non- Diabetic in Haemodialysis patients Qualitative difference
Detailed Description:
Diabetes mellitus DM is a metabolic disease a consequence of defects in insulin action secretion or both and there are complications associated with it such as nephropathy retinopathy neuropathy cardiovascular complications cerebrovascular and peripheral arterial disease Diabetic nephropathy which occurs in about one third of type 2 diabetic patients is the most common factor leading to end-stage renal disease ESRD A very common metabolic abnormality associated with diabetes is dyslipidemia which is characterized by a spectrum of quantitative and qualitative changes in lipids and lipoproteinsSeveral previous studies have pursued linking blood glucose levels to serum lipid activities The etiology of dyslipidemia appears to be centered on the increased large TAG-rich very low-density lipoprotein-cholesterol VLDL-C and its impaired clearance American diabetic association ADA defines dyslipidemia as hypercholesterolemia 200 mgdl of serum total cholesterol hypertriglyceridemia 150 mgdl of serum triglyceride reduced high density lipoprotein cholesterol HDL-C 40 mgdl for men and 50 mgdl for women elevated low density lipoprotein cholesterol LDL-C 70 mgdl and high TC to HDL-C ratio of 45 Normal plasma lipids and lipoprotein metabolism is critical for cellular cholesterol homeostasis and protection against atherosclerosis renal disease and other complication A study found that people with high blood pressure and overweight or obesity have a higher risk of developing dyslipidemia Early detection and effective control of blood lipid levels can reduce the morbidity and mortality of CVD in patients with DM Therefore it is important to determine the factors associated with dyslipidemia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None