Ignite Creation Date:
2024-05-11 @ 8:30 AM
Last Modification Date:
2025-12-16 @ 8:20 PM
Study NCT ID:
NCT06402734
Status:
None
Last Update Posted:
2024-05-07 00:00:00
First Post:
2024-05-03 00:00:00
Brief Title:
Effects of Gluten-Free Diet on Nutritional Status in Celiac Patients
Sponsor:
Hacettepe University
Organization:
Hacettepe University
Study Overview
Official Title:
Effects of Gluten-Free Diet on Nutritional Status and Inflammation Parameters in Adult Celiac Patients
Status:
None
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aimed to examine the effects of a gluten-free diet on the nutritional status, anthropometric measurements, and serum levels of interferon-gamma (IFN-γ) and interleukin-15 (IL-15) in adult celiac patients, comparing them with a control group. A total of 26 celiac patients aged 18-64 years and 26 healthy individuals as the control group were included. Face-to-face interviews were conducted to determine participants\' general characteristics, dietary habits, and physical activity status. Additionally, a retrospective 24-hour dietary recall and food frequency questionnaire were administered to assess dietary intake. Anthropometric measurements and blood samples were collected during the interviews. Celiac patients received education about the gluten-free diet, and follow-up assessments were conducted six weeks later. At the beginning, 53.8% of celiac patients reported always/mostly adhering to the gluten-free diet, which increased to 100.0% after six weeks. The total quality of life scores significantly increased in celiac patients after six weeks. Initial serum IL-15 levels were similar between celiac and control groups, whereas serum IFN-γ levels were significantly higher in celiac patients compared to the control group.
Detailed Description:
This study aimed to examine the effects of a gluten-free diet on the nutritional status anthropometric measurements and serum levels of interferon-gamma IFN-γ and interleukin-15 IL-15 in adult celiac patients comparing them with a control group A total of 26 celiac patients aged 18-64 years and 26 healthy individuals as the control group were included Face-to-face interviews were conducted to determine participants39 general characteristics dietary habits and physical activity status Additionally a retrospective 24-hour dietary recall and food frequency questionnaire were administered to assess dietary intake Anthropometric measurements and blood samples were collected during the interviews Celiac patients received education about the gluten-free diet and follow-up assessments were conducted six weeks later At the beginning 538 of celiac patients reported alwaysmostly adhering to the gluten-free diet which increased to 1000 after six weeks The total quality of life scores significantly increased in celiac patients after six weeks Initial serum IL-15 levels were similar between celiac and control groups whereas serum IFN-γ levels were significantly higher in celiac patients compared to the control group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None