Ignite Creation Date:
2024-05-11 @ 8:30 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06409949
Status:
RECRUITING
Last Update Posted:
2024-05-10
First Post:
2024-04-17
Brief Title:
MitoQ Treatment of Claudication Myofiber and Micro-vessel Pathology
Sponsor:
University of Nebraska
Organization:
University of Nebraska
Study Overview
Official Title:
MitoQ Treatment of Claudication Myofiber and Micro-vessel Pathology
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In our research we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease especially those who suffer from leg pain while walking known as intermittent claudication We will be checking if MitoQ helps people with claudication walk better be more active every day feel better about their lives and if it enhances the health of their leg muscles
Detailed Description:
This study will investigate whether taking MitoQ for six months can improve the walking ability daily activity levels and quality of life of people with claudication leg pain caused by peripheral artery disease PAD Well also look at how MitoQ affects their calf muscles
Heres what well be checking
Muscle health Well examine muscle tissue samples under a microscope to see if MitoQ improves muscle health and function
Body chemistry Well check blood tests to see if MitoQ affects overall health markers
Mitochondrial health Well see if MitoQ reduces damage to mitochondria the cells powerhouses and helps the body get rid of damaged ones Well also see if it improves how well mitochondria function
Blood flow Well measure blood flow in the legs and see if MitoQ improves the function of tiny blood vessels in the calf muscles
In short we want to see if MitoQ can improve various aspects of health in people with claudication and PAD and if these improvements are linked to better functioning mitochondria in their muscles
Heres what well be checking
Muscle health Well examine muscle tissue samples under a microscope to see if MitoQ improves muscle health and function
Body chemistry Well check blood tests to see if MitoQ affects overall health markers
Mitochondrial health Well see if MitoQ reduces damage to mitochondria the cells powerhouses and helps the body get rid of damaged ones Well also see if it improves how well mitochondria function
Blood flow Well measure blood flow in the legs and see if MitoQ improves the function of tiny blood vessels in the calf muscles
In short we want to see if MitoQ can improve various aspects of health in people with claudication and PAD and if these improvements are linked to better functioning mitochondria in their muscles
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None