Ignite Creation Date:
2024-05-06 @ 8:28 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06398899
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-03
First Post:
2024-03-05
Brief Title:
Sugammadex vs NeostigmineGlycopyrrolate
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
Sugammadex Compared With NeostigmineGlycopyrrolate in Impact of Postoperative Urinary Retention for Head and Neck Surgery Patients With High Risk of Dysuria
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of study is to clarify the role of sugammadex in head and neck surgery patients with a prior history of urinary retention benign prostatic hypertrophy or a history of prostate cancer to prevent postoperative urinary retention The main question it aims to answer are
Anticholinergic agent interferes the postoperative urination
Sugammadex does not interfere postoperative urination Sugammadex can be recommended for these patients with high risk in postoperative urinary retention in the future
Anticholinergic agent interferes the postoperative urination
Sugammadex does not interfere postoperative urination Sugammadex can be recommended for these patients with high risk in postoperative urinary retention in the future
Detailed Description:
Investigators will evaluate the benefit of sugammadex in reducing postoperative urinary retention for these head and neck surgery patients with high-risk for dysuria The definition of high-risk of dysuria is patient with a prior history of urinary retention benign prostatic hypertrophy or a history of prostate cancer
Patients scheduled to undergo head and neck surgery within two hours of expected surgical time are enrolled These patients are associated with high-risk of postoperative urinary retention including prior history of urinary retention benign prostatic hypertrophy or a history of prostate cancer They are randomly divided these patients into sugammadex group S group and neostigmineglycopyrrolate group Group N sugammadex or neostigmineglycopyrrolate are used during recovery period of anesthesia to compare the incidences of postoperative urinary retention nauseavomiting bradycardia hypotension and dry mouth in these patients after head and neck surgery Sugammadex can be recommended for these high-risk patients in the future
Patients scheduled to undergo head and neck surgery within two hours of expected surgical time are enrolled These patients are associated with high-risk of postoperative urinary retention including prior history of urinary retention benign prostatic hypertrophy or a history of prostate cancer They are randomly divided these patients into sugammadex group S group and neostigmineglycopyrrolate group Group N sugammadex or neostigmineglycopyrrolate are used during recovery period of anesthesia to compare the incidences of postoperative urinary retention nauseavomiting bradycardia hypotension and dry mouth in these patients after head and neck surgery Sugammadex can be recommended for these high-risk patients in the future
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None