Ignite Creation Date:
2024-05-06 @ 8:28 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06395818
Status:
COMPLETED
Last Update Posted:
2024-05-02
First Post:
2024-04-29
Brief Title:
the Effect of Hyaluronic Acid on a Prefabricated CAD-CAM Bone Blocks for Ridge Augmentation
Sponsor:
Tanta University
Organization:
Tanta University
Study Overview
Official Title:
the Effect of Hyaluronic Acid on a Prefabricated CAD-CAM Bone Blocks for Ridge Augmentation Radiographically and Histologically
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Each patient will receive 2 prefabricated CAD-CAM allogeneic bone blocks sterilized with gamma rays with different rehydration methods
Side I prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using hyaluronic acid Side II prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using saline solution Both blocks are fixed with osteosynthesis screws covered with non resorbable membranes The membranes will be removed after 5 months dental implants will be placed and core biopsy will be collected from the site of the implant placement for histologic evaluation
Side I prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using hyaluronic acid Side II prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using saline solution Both blocks are fixed with osteosynthesis screws covered with non resorbable membranes The membranes will be removed after 5 months dental implants will be placed and core biopsy will be collected from the site of the implant placement for histologic evaluation
Detailed Description:
12 patients will be included in this study with bilateral atrophic posterior mandible for split mouth research
Side I prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using hyaluronic acid Side II prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using saline solution under LA mucoperiosteal flap will be elevated to expose the atrophic ridge then the prefabricated CAD-CAM allogenic block will be fixed in its position with titanium miniscrews autogenous bone graft will be taken from the ramus and either mixed with hyaluronic acid side I or saline side II to cover the allogenic block then closure of flap with nylon second stage 5 months later exposure of alveolar ridge core biopsy was takrn for histological study then insertion of titanium implants
the aim of the study is to investigate the effect of hyaluronic acid on a prefabricated CAD- CAM bone blocks for ridge augmentation radiographically and histologically
Side I prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using hyaluronic acid Side II prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using saline solution under LA mucoperiosteal flap will be elevated to expose the atrophic ridge then the prefabricated CAD-CAM allogenic block will be fixed in its position with titanium miniscrews autogenous bone graft will be taken from the ramus and either mixed with hyaluronic acid side I or saline side II to cover the allogenic block then closure of flap with nylon second stage 5 months later exposure of alveolar ridge core biopsy was takrn for histological study then insertion of titanium implants
the aim of the study is to investigate the effect of hyaluronic acid on a prefabricated CAD- CAM bone blocks for ridge augmentation radiographically and histologically
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None