Ignite Creation Date:
2024-05-06 @ 8:28 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06395974
Status:
RECRUITING
Last Update Posted:
2024-05-02
First Post:
2024-04-29
Brief Title:
Fetal Renal Artery Doppler in Patients With Preeclampsia
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Fetal Renal Artery Doppler in Patients With Preeclampsia and Its Role in Prediction of Adverse Neonatal Outcomes
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Preeclampsia is a major devastating disorder affects 210 of pregnancies worldwide preeclampsia may be associated with placental insufficiency which may cause fetal blood redistribution to essential organs like brain heart kidney
Detailed Description:
Preeclampsia is a major devastating medical condition that affects pregnant women after 20 weeks of pregnancy It affects 210 of pregnancies worldwide according to World Health Organisation with higher incidence in developing countries
Vascular endothelial dysfunction due to abnormal placentation is believed to be the main cause of multi-organ failure and uteroplacental insufficiency that occur in preeclampsia leading to major adverse effects in both mother and fetus
Placental insufficiency causes a redistribution of fetal blood to essential organs brain heart and adrenal glands by decreasing their vascular resistance on expense of peripheral organs such as kidney which exhibit increased vascular resistance and impaired perfusion This is in contrast to normal pregnancies near term in which renal vascular resistance falls and increased blood flow to the kidneys is observed Doppler ultrasound examination of vasculature of selected organs such as kidneys may have a role in detection of hemodynamic rearrangements that occur in cases of placental insufficiency and preeclampsia
Vascular endothelial dysfunction due to abnormal placentation is believed to be the main cause of multi-organ failure and uteroplacental insufficiency that occur in preeclampsia leading to major adverse effects in both mother and fetus
Placental insufficiency causes a redistribution of fetal blood to essential organs brain heart and adrenal glands by decreasing their vascular resistance on expense of peripheral organs such as kidney which exhibit increased vascular resistance and impaired perfusion This is in contrast to normal pregnancies near term in which renal vascular resistance falls and increased blood flow to the kidneys is observed Doppler ultrasound examination of vasculature of selected organs such as kidneys may have a role in detection of hemodynamic rearrangements that occur in cases of placental insufficiency and preeclampsia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None