Ignite Creation Date:
2024-05-06 @ 8:28 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06398691
Status:
COMPLETED
Last Update Posted:
2024-05-03
First Post:
2024-03-15
Brief Title:
Premature Newborns Treated With Less Invasive Surfactant Administration Under Heated Humidified High-flow
Sponsor:
Hacettepe University
Organization:
Hacettepe University
Study Overview
Official Title:
Is it Possible to Premature Newborns Treated With Less Invasive Surfactant Administration Under Heated Humidified High-flow Air With Nasal Cannula
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Nasal Continuous Airway Pressure CPAP or Heated humidified high-flow Air support with nasal cannula HHHFNC are among the most commonly used non-invasive respiratory support methods The purpose of this prospective study was to compare vital findings blood gas parameters perfusion index PI and plethysmographic variability index PVI values in premature infants treated with less invasive surfactant administration LISA under HHHFNC or CPAP
Detailed Description:
Nasal Continuous Airway Pressure CPAP or Heated humidified high-flow Air support with nasal cannula HHHFNC are among the most commonly used non-invasive respiratory support methods The purpose of this prospective study was to compare vital findings blood gas parameters perfusion index PI and plethysmographic variability index PVI values in premature infants treated with less invasive surfactant administration LISA under HHHFNC or CPAP This study was carried out in Hacettepe University Hospital NICU between January and December 2017 Premature newborns who were on noninvazive respiratory support and were diagnosed as RDS within first 72 hours of life were taken into the study Noninvasive respiratory support was provided with nasal CPAP or HHHNFC Pulse oxymetry measurements were obtained before and 5th 30th 60th 120th 360th minutes blood gas analysis was performed immediately before and 120th 360th minutes after surfactant administration
Post-hoc one-way difference between two independent means two groups statistical analysis was used Significance P 005 effect size 09 power 1-ß err prob was found to be 82
Post-hoc one-way difference between two independent means two groups statistical analysis was used Significance P 005 effect size 09 power 1-ß err prob was found to be 82
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None