Ignite Creation Date:
2024-05-06 @ 8:27 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06399120
Status:
RECRUITING
Last Update Posted:
2024-05-06
First Post:
2024-04-29
Brief Title:
Diagnostic Performance of Endocytoscopy for Colorectal Lesions
Sponsor:
The First Hospital of Jilin University
Organization:
The First Hospital of Jilin University
Study Overview
Official Title:
Diagnostic Performance of Endocytoscopy for Colorectal Lesions
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Colorectal cancer is the third most common malignancy worldwide and the second leading cause of cancer-related death About 70 of colorectal cancers develop through the adenoma-cancer pathway Early detection and resection of colorectal neoplastic lesions significantly reduce the morbidity and mortality of colorectal cancers Colonoscopy is considered to be the preferred method for screening for colorectal lesions However as the number of endoscopic resection increases the costs associated with pathological diagnosis of endoscopic resection and resection specimens increase year by year In clinical practice it will be very important and urgent to correctly judge the nature of colorectal lesions to avoid pathological diagnosis and then realize optical biopsy Therefore to clarify the endoscopic diagnosis of colorectal lesions many endoscopic techniques have been applied clinically Such as narrow-band imaging magnifying narrow-band imaging endoscopy magnifying chromoendoscopy and endocytoscopy Endocytoscopy has two modes EC-NBI mode and EC-staining mode EC-NBI mode is to observe the microvessel on the mucosal surface of colorectal mucosa after switching the endoscopy to NBI mode EC-V pattern is used to observe microvessels and then endoscopic diagnosis is performed The EC-staining mode was that the cell nuclei and glandular duct morphology of colorectal lesions could be observed by endocytoscopy after chemical staining Endocytoscopic diagnosis is performed clinically after observation of glandular ducts and nuclei However current studies on the diagnostic value of endoscopy in colorectal lesions are all retrospective studies with small samples and there is a lack of clinical studies based on chinese population Therefore our center intends to conduct a study of a large sample to explore the diagnostic value of endoscopy in colorectal lesions
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None