Ignite Creation Date:
2024-05-06 @ 8:27 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06394544
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-01
First Post:
2024-04-27
Brief Title:
Effects of Brazil Nut Supplementation in Patients With Chronic Kidney Disease Undergoing Conservative Treatment
Sponsor:
Universidade Federal Fluminense
Organization:
Universidade Federal Fluminense
Study Overview
Official Title:
Effects of Brazil Nut Supplementation on Inflammation Oxidative Stress and Microbiota in Patients With Chronic Kidney Disease Undergoing Conservative Treatment
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to evaluate the effects of Brazil nut supplementation on inflammation oxidative stress and intestinal microbiota in patients with chronic kidney disease undergoing conservative treatment
Detailed Description:
Complications such as inflammation and oxidative stress are common in chronic kidney disease CKD and directly influence the rate of disease progression Patients with CKD also have intestinal dysbiosis which aggravates the inflammatory process and oxidative stress forming a vicious circle between inflammation oxidative stress and intestinal dysbiosis Nutritional strategies try to alleviate this circle and Brazil nuts rich in bioactive compounds have already been proven effective in mitigating inflammation and oxidative stress in CKD patients on dialysis However to date the effectiveness of Brazil nuts in patients with CKD in stages prior to dialysis conservative treatment has not been tested The bioactive compounds in Brazil nuts are expected to contribute positively to the redox balance reduction of inflammation and intestinal eubiosis in patients with CKD undergoing conservative treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None