Ignite Creation Date:
2024-05-06 @ 8:27 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06388837
Status:
COMPLETED
Last Update Posted:
2024-04-29
First Post:
2024-04-24
Brief Title:
Effect of Symphysis Onlay Bone Graft Injectable Platelet Rich Fibrin I-PRF and Xenograft on Horizontal Alveolar Ridge Augmentation in Esthetic Zone
Sponsor:
October 6 University
Organization:
October 6 University
Study Overview
Official Title:
Evaluation of the Effect of Symphysis Onlay Bone Graft Injectable Platelet Rich Fibrin I-PRF and Xenograft on Horizontal Alveolar Ridge Augmentation in Esthetic Zone A Retrospective Study
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the study was to evaluate whether mandibular symphysis Onlay autogenous bone graft mixed with Injectable PRF could offer any advantages for patients undergoing horizontal alveolar ridge widening regarding increase alveolar ridge width compared to mandibular symphysis Onlay autogenous bone graft mixed with Xenograft
Detailed Description:
Alveolar bone resorption is one of complications post-extraction complications where there is a reduction in the dimensions and quality of the alveolar bone Alveolar bone resorption is known to occur over time but resorption in the first few months of tooth extraction is known to be very significant
The ideal bone graft material should have osteoconductive osteogenic and osteoinductive properties and mechanical stability and be free from disease Osteoconductive is a physical property of a material that provides a framework for the growth of blood vessels and osteoprogenitor cells in bone formation Osteoinductiveness is the ability to stimulate stem cells to differentiate in mature cells through stimulation by local growth factors Osteogenicity is the bone growth factors in bone grafts
Growth factors from PRF such as platelet-derived growth factor PDGF transforming growth factor TGF and insulin growth factor IGF are known to play a significant role in healing and bone regeneration to prevent excessive alveolar resorption after tooth extraction
The ideal bone graft material should have osteoconductive osteogenic and osteoinductive properties and mechanical stability and be free from disease Osteoconductive is a physical property of a material that provides a framework for the growth of blood vessels and osteoprogenitor cells in bone formation Osteoinductiveness is the ability to stimulate stem cells to differentiate in mature cells through stimulation by local growth factors Osteogenicity is the bone growth factors in bone grafts
Growth factors from PRF such as platelet-derived growth factor PDGF transforming growth factor TGF and insulin growth factor IGF are known to play a significant role in healing and bone regeneration to prevent excessive alveolar resorption after tooth extraction
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None