Ignite Creation Date:
2024-05-06 @ 8:26 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06381258
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-24
First Post:
2024-04-19
Brief Title:
Fetal Cardiac Function
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Fetal Systolic and Diastolic Cardiac Function Assessment in Mothers With Preeclampsia
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of our study is to evaluate the effect of PE and FGR on fetal cardiac function Pregnancies with preeclampsia and FGR and preeclampsia with normal fetal growth are evaluated by echocardiography and compared with uncomplicated pregnancies
Detailed Description:
Preeclampsia PE represent a major concern in public health affecting 2-8 of all pregnancies and considered one of the leading causes of perinatal morbidity and mortality Fetal growth restriction FGR ia also a common health problem affecting about 5-10 of all pregnancies and commonly associates with preeclampsia It is estimated that 20 of cases of PE present with FGR and about 50 of early-onset FGR cases will eventually coexist with PE
Both syndromes share some pathophysiologic features with a variable involvement of placental insufficiency and cause fetal cardiovascular remodeling and adaptations Fetal adaptations as metabolic and cardiovascular programming occur in response to adverse intrauterine conditions as PE and FGR Offspring from preeclamptic pregnancies showed cardiac structural and functional changes and greater blood pressure in childhood and adolescence
Most of the studies on FGR included pregnancies complicated by PE and vice versa which fails to adequately assess the independent effect of each condition on the fetal cardiac functions
Both syndromes share some pathophysiologic features with a variable involvement of placental insufficiency and cause fetal cardiovascular remodeling and adaptations Fetal adaptations as metabolic and cardiovascular programming occur in response to adverse intrauterine conditions as PE and FGR Offspring from preeclamptic pregnancies showed cardiac structural and functional changes and greater blood pressure in childhood and adolescence
Most of the studies on FGR included pregnancies complicated by PE and vice versa which fails to adequately assess the independent effect of each condition on the fetal cardiac functions
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None