Ignite Creation Date:
2024-05-06 @ 8:26 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06388486
Status:
COMPLETED
Last Update Posted:
2024-04-30
First Post:
2024-04-23
Brief Title:
Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy
Sponsor:
University Medical Center Goettingen
Organization:
University Medical Center Goettingen
Study Overview
Official Title:
Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CitDip
Brief Summary:
The goal of this observational study is to measure the levels of cytokine-induced transcription factor activation in a cohort of depressed inpatients undergoing psychotherapy The study aims to answer the following main questions
Do psychological traits ie social inhibition negative affectivity affect the activation of immunomodulatory transcription factors STAT3 NFkB in depressed patients
Are subjects with these psychological traits affected differently by psychotherapeutic intervention
Study subjects are assessed for their psychological and behavioral traits and receive psychotherapeutic care over several weeks during hospital treatment Peripheral blood mononuclear cells are isolated from the study subjects and activation of transcription factors is measured by flow cytometry
Do psychological traits ie social inhibition negative affectivity affect the activation of immunomodulatory transcription factors STAT3 NFkB in depressed patients
Are subjects with these psychological traits affected differently by psychotherapeutic intervention
Study subjects are assessed for their psychological and behavioral traits and receive psychotherapeutic care over several weeks during hospital treatment Peripheral blood mononuclear cells are isolated from the study subjects and activation of transcription factors is measured by flow cytometry
Detailed Description:
Study subjects are assessed for their psychological and behavioral traits and receive psychotherapeutic care over several weeks during hospital treatment Peripheral blood mononuclear cells are isolated from the study subjects and activation of transcription factors is measured by flow cytometry
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None