Ignite Creation Date:
2025-12-24 @ 7:41 PM
Ignite Modification Date:
2026-01-01 @ 8:14 AM
Study NCT ID:
NCT07108803
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2025-08-07
First Post:
2025-07-16
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis
Sponsor:
Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI)
Organization:
Study Overview
Official Title:
European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE)
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2025-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ERGOSTE
Brief Summary:
The European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE) is a nascent large surgical registry that would encompass most relevant aspects of IE in Europe in the contemporary era.
Detailed Description:
ERGOSTE, Purposes:
* To create a European multicenter retrospective database including a large number of patients undergoing surgical treatment for infective endocarditis (IE).
* To perform epidemiologic analyses of IE-patients and involved pathogens.
* To find independent predictors of early post-operative death.
* To test ALL the scoring systems specifically developed to predict early death after surgery for infective endocarditis.
* To devise a specific risk score for early postoperative death.
* To explore early and late outcomes of these very difficult patients in order to establish optimal indications, techniques and timing of surgery.
* To carry out a number of sub-analyses concerning the demographic parameters and variable clinical presentation of patients, type and severity of cardiac structural involvement, adopted valve prostheses and surgical techniques, and different involved microbiologic agents.
* To lay experiential foundations of a prospective database on the topic.
* To create a European multicenter retrospective database including a large number of patients undergoing surgical treatment for infective endocarditis (IE).
* To perform epidemiologic analyses of IE-patients and involved pathogens.
* To find independent predictors of early post-operative death.
* To test ALL the scoring systems specifically developed to predict early death after surgery for infective endocarditis.
* To devise a specific risk score for early postoperative death.
* To explore early and late outcomes of these very difficult patients in order to establish optimal indications, techniques and timing of surgery.
* To carry out a number of sub-analyses concerning the demographic parameters and variable clinical presentation of patients, type and severity of cardiac structural involvement, adopted valve prostheses and surgical techniques, and different involved microbiologic agents.
* To lay experiential foundations of a prospective database on the topic.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: