Ignite Creation Date:
2024-05-06 @ 8:26 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06384495
Status:
RECRUITING
Last Update Posted:
2024-04-25
First Post:
2024-04-22
Brief Title:
How Does Cerebellar tDCS Alter Intracortical Inhibition Over Time
Sponsor:
University of Minnesota
Organization:
University of Minnesota
Study Overview
Official Title:
How Does Cerebellar tDCS Alter Intracortical Inhibition Over Time
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Combining cortical tDCS with behavioral interventions has been shown to have beneficial outcomes in individuals post-stroke However cerebellar tDCS is a fairly new approach for individuals with unilateral cortical stroke and there has not been reports of duration of effect of tDCS applied to the cerebellum in this population
Information gained from this study will serve to fill knowledge gaps on the duration of effect of cerebellar tDCS and the effects of polarity
The purpose of this study is to determine the duration of effect of ventro-lateral cerebellar transcranial direct current stimulation tDCS in healthy adults through cortical excitability CE cognitive language and motor assessment measures Primary aim Compare baseline CE from left motor cortex of first dorsal interosseous FDI and orbicularis oris OO areas to CE post cerebellar tDCS at 15 minutes 45 minutes and 75 minutes Single-pulse and paired-pulse transcranial magnetic stimulation TMS will be used to measure and compare stimulus response curve SR curve cortical silent period CSP and short-interval intracortical inhibition SICI in the hand area and facial area of the left primary motor cortex at each time point
Secondary aim Compare baseline performance on cognition motor learning and language tasks to performance at 15 45 and 75 minutes after receiving tDCS Digit Symbol Substitution Test DSST Serial Reaction Time Test SRTT and Lexical Decision tasks will be presented via a computer interface
Information gained from this study will serve to fill knowledge gaps on the duration of effect of cerebellar tDCS and the effects of polarity
The purpose of this study is to determine the duration of effect of ventro-lateral cerebellar transcranial direct current stimulation tDCS in healthy adults through cortical excitability CE cognitive language and motor assessment measures Primary aim Compare baseline CE from left motor cortex of first dorsal interosseous FDI and orbicularis oris OO areas to CE post cerebellar tDCS at 15 minutes 45 minutes and 75 minutes Single-pulse and paired-pulse transcranial magnetic stimulation TMS will be used to measure and compare stimulus response curve SR curve cortical silent period CSP and short-interval intracortical inhibition SICI in the hand area and facial area of the left primary motor cortex at each time point
Secondary aim Compare baseline performance on cognition motor learning and language tasks to performance at 15 45 and 75 minutes after receiving tDCS Digit Symbol Substitution Test DSST Serial Reaction Time Test SRTT and Lexical Decision tasks will be presented via a computer interface
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None