Ignite Creation Date:
2024-05-06 @ 8:26 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06383130
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-25
First Post:
2024-04-19
Brief Title:
London Asthma Diagnostics Study
Sponsor:
Imperial College London
Organization:
Imperial College London
Study Overview
Official Title:
A Pragmatic Diagnostic Accuracy Study of a Triple Diagnostic Approach and Exploratory Biomarkers in Adult Asthma Diagnosis
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LADS
Brief Summary:
The goal of this trial is to learn if the addition of oscillometry with reversibility testing increases diagnostic accuracy in adult asthma diagnosis when added to current standard of care tests spirometry with reversibility testing and Fractional Exhaled Nitric Oxide FeNO The main question it aims to answer is
- Does oscillometry with reversibility testing increase diagnostic accuracy in detection of asthma in adults when added to spirometry with reversibility and FeNO
Researchers will evaluate the diagnostic accuracy of this approach with the reference standard which is a clinically adjudicated diagnosis of asthma by two respiratory clinicians based on history and investigation results
Participants will
Undergo oscillometry testing alongside their routine asthma investigations within their scheduled clinic visit
Optionally participate in our sub-studies on new breath and nasal swab tests for asthma
Optionally participate in our qualitative substudy on patients views and attitudes to asthma testing and oscillometry
- Does oscillometry with reversibility testing increase diagnostic accuracy in detection of asthma in adults when added to spirometry with reversibility and FeNO
Researchers will evaluate the diagnostic accuracy of this approach with the reference standard which is a clinically adjudicated diagnosis of asthma by two respiratory clinicians based on history and investigation results
Participants will
Undergo oscillometry testing alongside their routine asthma investigations within their scheduled clinic visit
Optionally participate in our sub-studies on new breath and nasal swab tests for asthma
Optionally participate in our qualitative substudy on patients views and attitudes to asthma testing and oscillometry
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None