Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06372886
Status:
COMPLETED
Last Update Posted:
2024-04-18
First Post:
2024-04-08
Brief Title:
Clinical Outcomes of Preservation Versus Resection of PortalSuperior Mesenteric Vein During Pancreaticoduodenectomy in Pancreatic Cancer Patients Who Respond to Neoadjuvant Treatment
Sponsor:
Seoul National University Hospital
Organization:
Seoul National University Hospital
Study Overview
Official Title:
Clinical Outcomes of Preservation Versus Resection of PortalSuperior Mesenteric Vein During Pancreaticoduodenectomy in Pancreatic Cancer Patients Who Respond to Neoadjuvant Treatment
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
1 There is a lack of evidence on the need to perform portalsuperior mesenteric vein PVSMV resection routinely in pancreatic ductal adenocarcinoma PDAC patients with venous involvement who responded to neoadjuvant treatment NAT
2 There is no significant differences in R0 rate 5-year overall survival and recurrence-free survival between the PVSMV preservation PVP group and PVSMV resection PVR group
3 PVP group showed significantly better 5-year PVSMV stenosis free survival than the PVR group
4 We propose that if dissection is possible and there is a high likelihood of achieving R0 resection after NAT routine PVR may be unnecessary in PDAC patients with venous involvement
2 There is no significant differences in R0 rate 5-year overall survival and recurrence-free survival between the PVSMV preservation PVP group and PVSMV resection PVR group
3 PVP group showed significantly better 5-year PVSMV stenosis free survival than the PVR group
4 We propose that if dissection is possible and there is a high likelihood of achieving R0 resection after NAT routine PVR may be unnecessary in PDAC patients with venous involvement
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None