Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06370403
Status:
COMPLETED
Last Update Posted:
2024-04-19
First Post:
2024-04-11
Brief Title:
Effects of Head and Neck Cooling and Heating on Fatigue in Multiple Sclerosis and Healthy Men
Sponsor:
Lithuanian Sports University
Organization:
Lithuanian Sports University
Study Overview
Official Title:
Effects of Head and Neck Cooling and Heating on Central and Peripheral Fatigue Motor Accuracy and Blood Markers of Stress in Multiple Sclerosis and Healthy Men
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Local head and neck cooling strategies can help reduce multiple sclerosis-related fatigue while heating can exacerbate heat-related fatigue However no study has detailed the peripheral and central responses to head and neck cooling at 18C and heating at 43 1C next to the scalp and neck skin during fatiguing isometric exercise in non-challenging ambient temperature in multiple sclerosis and healthy male subjects In addition there is a lack of data describing the effects of head and neck coolingheating and strenuous exercise on blood markers muscle temperature motor accuracy and rate of perceived exertion The investigators hypothesized that i men with multiple sclerosis would be more affected by central and peripheral fatigue compared to healthy subjects ii local cooling will result in greater central fatigue but will be associated with greater peripheral fatigue whereas heating will result in greater central and peripheral fatigue in multiple sclerosis men iv local cooling and heating will have a greater effect on the release of stress hormones rate of perceived exertion and motor accuracy compared to the control condition in both multiple sclerosis and healthy groups
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None