Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06374017
Status:
RECRUITING
Last Update Posted:
2024-04-18
First Post:
2024-04-11
Brief Title:
Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response
Sponsor:
Kasr El Aini Hospital
Organization:
Kasr El Aini Hospital
Study Overview
Official Title:
Evaluating the Effect of Topical Lidocaine Spray Versus Dexmedetomidine Spray on Suppression of Stress Response to Laryngoscopy and Endotracheal Intubation a Randomized Controlled Study
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Many studies discussed attenuating stress response by various measures but to the interest of our study No one compared topical spray of both lidocaine and dexmedetomidine in attenuating the haemodynamic stress responses of laryngoscopy and endotracheal intubation avoiding undesired systemic effects of drugs
Detailed Description:
This study will be conducted in the operating theatres of Cairo university hospitals
Patients undergoing any surgery under general anesthesia and needs endotracheal intubation using direct laryngoscopy will be assigned to one of the three groups
Group C will receive 5ml of normal saline sprayed via long nostril syringe into oropharynx the vocal cords and tracheobronchial tree 5 minutes before intubation Group L will receive 5ml of lidocaine 2 100mg sprayed via long nostril syringe into oropharynx the vocal cords and tracheobronchial tree 5 minutes before intubation Group D will receive dexmedetomidine 1 μgkg diluted in 5ml normal saline sprayed via long nostril syringe into oropharynx the vocal cords and tracheobronchial tree 5 minutes before intubation
Patients undergoing any surgery under general anesthesia and needs endotracheal intubation using direct laryngoscopy will be assigned to one of the three groups
Group C will receive 5ml of normal saline sprayed via long nostril syringe into oropharynx the vocal cords and tracheobronchial tree 5 minutes before intubation Group L will receive 5ml of lidocaine 2 100mg sprayed via long nostril syringe into oropharynx the vocal cords and tracheobronchial tree 5 minutes before intubation Group D will receive dexmedetomidine 1 μgkg diluted in 5ml normal saline sprayed via long nostril syringe into oropharynx the vocal cords and tracheobronchial tree 5 minutes before intubation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None