Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06375902
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-19
First Post:
2024-03-15
Brief Title:
The Fragility of Metaphors FraMe Learning Loosing and How to Train Them
Sponsor:
IRCCS San Raffaele
Organization:
IRCCS San Raffaele
Study Overview
Official Title:
The Fragility of Metaphors FraMe Learning Loosing and How to Train Them
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FRAME
Brief Summary:
Tracking down the difficulties in metaphor comprehension experienced by individuals with schizophrenia across different metaphor types and exploring the neurological correlates via EEG recording technique
Detailed Description:
The investigators will address the following objectives
Primary Objective Tracking down the difficulties in metaphor comprehension experienced by individuals with schizophrenia across different metaphor types and exploring the neurological correlates via EEG recording technique
Secondary Objectives 1 Evaluate the interactions between performances in metaphor comprehension and individual differences in psychopathology cognition ToM and functioning 2 Test if the altered neurophysiological patterns associated to the fragility of metaphor comprehension in schizophrenia can be restored through a rehabilitative training
The investigators will enroll 32 schizophrenic patients and 32 healthy subjects as control sample
Participants will undergo an initial visit with a specialist psychiatrist who will verify that their conditions meet the criteria required by the study Then subjects will be tested for metaphor comprehension as well as for the other variables included in the study and the electrical brain activity will be registered through a 128 channel EEG
In the check-up visits ie after the training the following data will be collected
Scores relating to cognitive pragmatic understanding of metaphors theory of mind and global functioning performance scores
EEG recordings related to the process of understanding metaphors
Scores on scales that evaluate psychopathological severity
Primary Objective Tracking down the difficulties in metaphor comprehension experienced by individuals with schizophrenia across different metaphor types and exploring the neurological correlates via EEG recording technique
Secondary Objectives 1 Evaluate the interactions between performances in metaphor comprehension and individual differences in psychopathology cognition ToM and functioning 2 Test if the altered neurophysiological patterns associated to the fragility of metaphor comprehension in schizophrenia can be restored through a rehabilitative training
The investigators will enroll 32 schizophrenic patients and 32 healthy subjects as control sample
Participants will undergo an initial visit with a specialist psychiatrist who will verify that their conditions meet the criteria required by the study Then subjects will be tested for metaphor comprehension as well as for the other variables included in the study and the electrical brain activity will be registered through a 128 channel EEG
In the check-up visits ie after the training the following data will be collected
Scores relating to cognitive pragmatic understanding of metaphors theory of mind and global functioning performance scores
EEG recordings related to the process of understanding metaphors
Scores on scales that evaluate psychopathological severity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None