Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06371313
Status:
COMPLETED
Last Update Posted:
2024-04-17
First Post:
2024-04-07
Brief Title:
Endocrine Metabolic and Inflammatory Characteristics of Offspring of Mothers With PCOS Hyperandrogenism
Sponsor:
Guangdong Women and Children Hospital
Organization:
Guangdong Women and Children Hospital
Study Overview
Official Title:
Endocrine Metabolic and Inflammatory Characteristics of Offspring of Mothers With PCOS Hyperandrogenism A Cross-sectional Study
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a cross-sectional study to explore the endocrine metabolism and inflammatory characteristics of the offspring of mothers with PCOS hyperandrogenism in order to provide a theoretical basis for finding the cause of PCOS
Detailed Description:
This study randomly selected 20 women with PCOS and hyperandrogenism who gave birth to a singleton at term at Guangdong Maternal and Child Health Hospital from May 2023 to March 2024 and set them as the HA group In addition 22 healthy women were randomly selected as controls group the fasting blood glucose FPG level of the newborn39s peripheral blood and the androgen fasting insulin and inflammatory factor levels of the newborn39s umbilical cord blood were collected respectively
Among them the detection indicators of newborn umbilical cord blood include testosterone T androstenedione AND dehydroepiandrosterone sulfate DHEA-S sex hormone binding globulin SHBG free androgen index FAI Fasting insulin FINS white blood cell count WBC neutrophil count NEUT high-sensitivity C-reactive protein hs-CRP and interleukin IL-6
All collected data were statistically analyzed to compare the differences in levels of androgens fasting insulin and inflammatory factors in the umbilical cord blood of newborns in the HA group and the control group
Among them the detection indicators of newborn umbilical cord blood include testosterone T androstenedione AND dehydroepiandrosterone sulfate DHEA-S sex hormone binding globulin SHBG free androgen index FAI Fasting insulin FINS white blood cell count WBC neutrophil count NEUT high-sensitivity C-reactive protein hs-CRP and interleukin IL-6
All collected data were statistically analyzed to compare the differences in levels of androgens fasting insulin and inflammatory factors in the umbilical cord blood of newborns in the HA group and the control group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None