Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06379191
Status:
COMPLETED
Last Update Posted:
2024-04-23
First Post:
2024-02-25
Brief Title:
The Efficacy of WeChat-based Multidisciplinary Full-course Nutritional Management Program
Sponsor:
Peking Union Medical College Hospital
Organization:
Peking Union Medical College Hospital
Study Overview
Official Title:
The Efficacy of WeChat-based Multidisciplinary Full-course Nutritional Management Program on the Nutritional Status of Ovarian Cancer Patients Undergoing Chemotherapy a Randomized Controlled Trial
Status:
COMPLETED
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
As the most malignant type of cancer in the female reproductive system ovarian cancer OC has become the second leading cause of death among Chinese women Chemotherapy is the main treatment for OC patients and its numerous adverse effects can easily lead to malnutrition It is difficult to centrally manage OC patients in the intervals between chemotherapy The utility of WeChat an effective and more cost-efficient mobile tool in chronic disease management has been highlighted
Detailed Description:
Ovarian cancer OC is the most malignant type of tumor in the female reproductive system with poor prognosis According to the latest statistics there are 196000 estimated OC cases 45000 estimated new cases and 29000 estimated OC deaths in China making this disease become the second leading cause of death among Chinese women
Approximately 90 of patients with OC receive chemotherapy The carboplatin-paclitaxel combination as a first-line chemotherapy regimen for OC has shown considerable efficacy over the past 30 years Unfortunately one of the major adverse effects of chemotherapy is malnutrition Malnutrition is defined as a nutritional condition in which deficiencies of energy protein and other nutrients have measurable adverse effects on tissuebody form function and clinical outcomes The most common adverse effects of chemotherapy including anorexia altered taste and smell food aversions nausea and vomiting mucositis xerostomia constipation diarrhea and early satiety negatively affect nutritional status Malnutrition has been shown to be one of the leading causes of death in OC patients It not only severely diminishes the efficacy of treatment but leads to increased complications decreased quality of life prolonged hospitalization increased healthcare costs and shorter survival time However existing nutritional interventions lack personalized guidance for patients nutritional status and symptoms during chemotherapy In addition it is difficult to centrally manage patients who are homebound between chemotherapy Therefore the construction of personalized nutritional management programs and the development of innovative telemedicine interventions for OC patients undergoing chemotherapy has become an urgent issue
WeChat a very popular social application in China has more than 1 billion monthly active users It is easy to operate and offers multiple functions such as text and voice messaging free voice and video calls group chats subscription to public accounts and applets etc WeChat has been demonstrated to be an effective and more cost-efficient technological tool for chronic disease management Currently the application of WeChat in cancer patients mainly focuses on discharge follow-up symptom management cancer prevention and intervention of psychological problems The effect of WeChat application in nutritional management of cancer patients has not been explored Therefore the aim of this study was to implement a continuous follow-up strategy and health monitoring based on a WeChat platform for OC patients undergoing chemotherapy during the chemotherapy interval to ensure that each phase of chemotherapy is delivered on schedule and to improve the survival rate of cancer patients
Approximately 90 of patients with OC receive chemotherapy The carboplatin-paclitaxel combination as a first-line chemotherapy regimen for OC has shown considerable efficacy over the past 30 years Unfortunately one of the major adverse effects of chemotherapy is malnutrition Malnutrition is defined as a nutritional condition in which deficiencies of energy protein and other nutrients have measurable adverse effects on tissuebody form function and clinical outcomes The most common adverse effects of chemotherapy including anorexia altered taste and smell food aversions nausea and vomiting mucositis xerostomia constipation diarrhea and early satiety negatively affect nutritional status Malnutrition has been shown to be one of the leading causes of death in OC patients It not only severely diminishes the efficacy of treatment but leads to increased complications decreased quality of life prolonged hospitalization increased healthcare costs and shorter survival time However existing nutritional interventions lack personalized guidance for patients nutritional status and symptoms during chemotherapy In addition it is difficult to centrally manage patients who are homebound between chemotherapy Therefore the construction of personalized nutritional management programs and the development of innovative telemedicine interventions for OC patients undergoing chemotherapy has become an urgent issue
WeChat a very popular social application in China has more than 1 billion monthly active users It is easy to operate and offers multiple functions such as text and voice messaging free voice and video calls group chats subscription to public accounts and applets etc WeChat has been demonstrated to be an effective and more cost-efficient technological tool for chronic disease management Currently the application of WeChat in cancer patients mainly focuses on discharge follow-up symptom management cancer prevention and intervention of psychological problems The effect of WeChat application in nutritional management of cancer patients has not been explored Therefore the aim of this study was to implement a continuous follow-up strategy and health monitoring based on a WeChat platform for OC patients undergoing chemotherapy during the chemotherapy interval to ensure that each phase of chemotherapy is delivered on schedule and to improve the survival rate of cancer patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None