Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06379282
Status:
RECRUITING
Last Update Posted:
2024-04-24
First Post:
2024-02-09
Brief Title:
Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia
Sponsor:
University of Surrey
Organization:
University of Surrey
Study Overview
Official Title:
Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
HIT-CLL
Brief Summary:
This randomised control clinical trial aims to investigate the effects of exercise training and diet on physical and functional fitness and immunological and metabolic changes in adults with chronic lymphocytic leukaemia Investigators will randomise participants to either 12 weeks of supervisedsemi-supervised exercise only exercise nutritional guidance or no exercise
Detailed Description:
This study aims to perform a randomised control trial of exercise or exercise plus nutritional guidance on the physiological and immunological health of adults diagnosed with chronic lymphocytic leukaemia CLL Recruited participants will be randomised to either 12 weeks of an exercise-only program an exercise-plus nutritional guidance program or a no-exercise control group Fasting blood samples collected at Baseline and 12 weeks will measure absolute CLL cell counts immune function and inflammatory and metabolic biomarkers A series of physical fitness assessments will be assessed at baseline and 12 weeks to determine physiologic reserve and resilience against external stressors Additionally participants will be asked to return 12 weeks after completing the intervention to assess the legacy effects of the intervention on the same physiological and blood-based biomarkers of health
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None