Ignite Creation Date:
2024-05-05 @ 7:03 PM
Last Modification Date:
2024-10-26 @ 9:40 AM
Study NCT ID:
NCT00590629
Status:
COMPLETED
Last Update Posted:
2011-09-14
First Post:
2007-12-26
Brief Title:
Benefit of Elevation of HDL-C on Cardiovascular Outcomes in Women
Sponsor:
Cedars-Sinai Medical Center
Organization:
Cedars-Sinai Medical Center
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2007-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Several risk factors including high cholesterol contribute to heart disease We know that lowering triglycerides and raising HDL protective cholesterol in men reduces the risk for heart disease We expect that women will share this same benefit because the combination of high triglycerides and low HDL appears to be a more important risk for heart disease in women Niacin reduces triglycerides and raises HDL We also expect to see improvement in markers of inflammation and clot formation and blood vessel health which we hypothesize should all confer a reduced risk of heart disease in women
Women already taking lipid lowering statin will receive niacin therapy We will measure blood lipid levels markers of inflammation and clotting as well as a non-invasive measure of blood vessel reactivity After 3 months of therapy we will repeat these measures
Women already taking lipid lowering statin will receive niacin therapy We will measure blood lipid levels markers of inflammation and clotting as well as a non-invasive measure of blood vessel reactivity After 3 months of therapy we will repeat these measures
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| GCRC Grant MO1-RR00425 | None | None | None |