Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06370780
Status:
RECRUITING
Last Update Posted:
2024-06-13
First Post:
2024-04-10
Brief Title:
Exploring Predicting and Intervening on Long-term Viral Suppression Electronically
Sponsor:
University of California Los Angeles
Organization:
University of California Los Angeles
Study Overview
Official Title:
Exploring Predicting and Intervening on Long-term Viral Suppression Electronically
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EPI-LoVE
Brief Summary:
Despite the widespread availability of effective antiretroviral therapy ART in the United States there remains significant numbers of people living with HIV PLWH who fail to achieve and or maintain viral suppression VS Disparities persist with the lowest levels of VS among Black individuals people who use drugs youth ages 18-24 and people residing in rural areas Investigators will examine the syndemics underlying these outcomes including substance use mental health and barriers to HIV care including racial discrimination stigma and rural isolation
Detailed Description:
This study will follow a digital cohort via the REMAIN App The REMAIN App is adapted from the HealthMPowerment HMP platform and tailored to our focus populations unique needs Digital cohorts or eCohorts utilize the flexibility and capacity of the internet to complement traditional approaches to epidemiological research helping address some of the limitations and challenges associated with conventional cohort studies
Aim 1 of this study is to recruit and retain a geographically and demographically diverse cohort of PLWH who are sub optimally engaged in care and with a history of at high risk for or not currently virally suppressed Outcomes for this are levels of recruitment and retention to hit the study objectives to enroll 1000 PLWH at risk for or experiencing VNS and follow them for up to 48 months Aim 2 is to evaluate longitudinal patterns of care engagement within the cohort by modeling and advanced epidemiologic methods utilizing remote collection of biomarkers of HIV disease eg viral load online surveys and brief frequent app-based check-ins Outcomes include both those related to VS and engagement in care as well as engagement in the digital cohort
Aim 1 of this study is to recruit and retain a geographically and demographically diverse cohort of PLWH who are sub optimally engaged in care and with a history of at high risk for or not currently virally suppressed Outcomes for this are levels of recruitment and retention to hit the study objectives to enroll 1000 PLWH at risk for or experiencing VNS and follow them for up to 48 months Aim 2 is to evaluate longitudinal patterns of care engagement within the cohort by modeling and advanced epidemiologic methods utilizing remote collection of biomarkers of HIV disease eg viral load online surveys and brief frequent app-based check-ins Outcomes include both those related to VS and engagement in care as well as engagement in the digital cohort
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None