Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06378021
Status:
RECRUITING
Last Update Posted:
2024-04-22
First Post:
2024-03-22
Brief Title:
Role of Calcium Chloride Injection in Alleviating Atrial Fibrillation Post CABG
Sponsor:
Helwan University
Organization:
Helwan University
Study Overview
Official Title:
Post Operative Atrial Fibrillation Alleviation by Calcium Chloride Injection Into Cardiac Ganglionic Plexus During Coronary Artery Bypass Grafting
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study hypothesize that injecting calcium chloride CaCl2 into the major atrial ganglionated plexus GPs during on pump Coronary artery bypass graft CABG can reduce the incidence of Post operative Atrial fibrillation in the first 7 days after surgeryThe study is designed to be prospective interventional study two armed RCT for on pump CABG patient
The intervention arm will be injected with Calcium chloride in the four major atrial ganglionic plexus The control arm will be injected with sodium chloride to determine the effect of Calcium chloride on Post CABG Atrial fibrillation
The intervention arm will be injected with Calcium chloride in the four major atrial ganglionic plexus The control arm will be injected with sodium chloride to determine the effect of Calcium chloride on Post CABG Atrial fibrillation
Detailed Description:
This study hypothesize that injecting calcium chloride into the major atrial ganglionic plexus GPs during On pump Coronary artery bypass graft CABG can reduce the incidence of Post operative Atrial fibrillation by calcium-induced autonomic neurotoxicity the incidence of Post operative Atrial fibrillation can be reduced by suppressing the function of the major atrial GPs and the surrounding neural network that play an important role in initiating Post operative Atrial fibrillation The study is designed to be prospective interventional study two armed RCT for on pump CABG patient The plan of work will include dividing the patients into 2 randomized control groups In the intervention group patients will be injected with 5 Calcium chloride in the 4 Major atrial ganglionic plexus The other arm will be Coronary artery bypass graft patients who will be injected with sodium chloride 09 to compare the two groups to evaluate to evaluate the effect of Calcium chloride in post CABG atrial fibrillation between the 2 arms of the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None