Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06375395
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-19
First Post:
2024-01-01
Brief Title:
Boosting The Intervention Effect of Negative Memory Through tACS Stimulation
Sponsor:
Xuanwu Hospital Beijing
Organization:
Xuanwu Hospital Beijing
Study Overview
Official Title:
Research on Improving the Intervention Effect of Negative Memory Through tACS Enhanced Memory Technology
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The objectives of this study include 1 investigating the impact of negative memory substitution on an individuals other intellectual memories ie neutral memories and the underlying neurocognitive mechanisms 2 investigating the memory enhancement effect resulting from retrieval practice associated with memory substitution intervention along with an examination of the neurocognitive mechanisms responsible for this enhancement
Detailed Description:
This study will adopt two memory updating strategies retrieval practice and reactivation
A 5-day memory updating experimental paradigm is used
1 On the first day the old memory A-B linkage is learned where A represents a neutral word and B is either neutral or negative pictures half of each randomly scrambled
2 On the second day the old memory A-B association is consolidated again and after a 15-minute break the new memory A-C association is learned where A is still the word A used in the old memory A-B association on the first day and C is the new neutral and negative pictures half of each randomly scrambled and with inconsistent categories of C and B in each pair of AC and AB Immediately following this the new memories of the A-C conjunctions are updated using both Retrieval practice and Restudy control condition memory strategies
3 A-C is extractedlearned using both Retrieval practice and Restudy memory strategies on both day 3 and day 4
4 On the fifth day memory tests for associative memory strength gist and detail memory as well as emotional valence and strength are performed
A 5-day memory updating experimental paradigm is used
1 On the first day the old memory A-B linkage is learned where A represents a neutral word and B is either neutral or negative pictures half of each randomly scrambled
2 On the second day the old memory A-B association is consolidated again and after a 15-minute break the new memory A-C association is learned where A is still the word A used in the old memory A-B association on the first day and C is the new neutral and negative pictures half of each randomly scrambled and with inconsistent categories of C and B in each pair of AC and AB Immediately following this the new memories of the A-C conjunctions are updated using both Retrieval practice and Restudy control condition memory strategies
3 A-C is extractedlearned using both Retrieval practice and Restudy memory strategies on both day 3 and day 4
4 On the fifth day memory tests for associative memory strength gist and detail memory as well as emotional valence and strength are performed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None