Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06373328
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-18
First Post:
2024-04-11
Brief Title:
Post Pandemic Pneumococcal Carriage Among Children and Adults
Sponsor:
University of Central Florida
Organization:
University of Central Florida
Study Overview
Official Title:
Post-Pandemic Genomic Epidemiology of Pneumococcal Carriage Among Children and Adults in the General US Population
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The PI propose to conduct a genomic epidemiology study of pneumococcal carriage among children and adults in a large metropolitan city These data will allow PI to assess the post-pandemic population structure investigate the phylogenetic relationship between isolates from children and adults and compare pneumococcal populations across diverse geographic areas
Detailed Description:
The SARS-CoV-2 pandemic profoundly impacted human health directly and indirectly As such elucidating pre- and post-pandemic trends in the epidemiology and population genomics of human respiratory pathogens including those such as the bacteria Streptococcus pneumoniae a human commensal and the causative agent of invasive pneumococcal disease IPD merits study
Nasopharyngeal samples will be processed at the PIs Laboratory to identify S pneumoniae If present the isolate will undergo bacterial whole genome sequencings and population dynamic analysis Carriage prevalence and serotype composition will be compared to extant studies and pneumococcal genomic data will be analyzed in the context of samples from the US and abroad
Nasopharyngeal samples will be processed at the PIs Laboratory to identify S pneumoniae If present the isolate will undergo bacterial whole genome sequencings and population dynamic analysis Carriage prevalence and serotype composition will be compared to extant studies and pneumococcal genomic data will be analyzed in the context of samples from the US and abroad
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None